Acyclovir and Abnormal behaviour - a phase IV clinical study of FDA data

Summary:

Abnormal behaviour is reported as a side effect among people who take Acyclovir (acyclovir), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Omeprazole, and have Insomnia.

The phase IV clinical study analyzes which people have Abnormal behaviour when taking Acyclovir. It is created by eHealthMe based on reports of 53,484 people who have side effects when taking Acyclovir from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

What is Abnormal behaviour?

Abnormal behaviour is found to be associated with 1,880 drugs and 2,156 conditions by eHealthMe. Check the latest studies of Abnormal behaviour.

On Dec, 06, 2025

53,484 people reported to have side effects when taking Acyclovir.
Among them, 75 people (0.14%) have Abnormal behaviour.

Could Acyclovir cause Abnormal behaviour?

Among these 75 people:

How long have people been on Acyclovir when they have Abnormal behaviour? *

What is the gender of people who have Abnormal behaviour when taking Acyclovir? *

female: 37.14 %
male: 62.86 %

What is the age of people who have Abnormal behaviour when taking Acyclovir? *

What are other drugs people take besides Acyclovir? *

What are other side effects people have besides Abnormal behaviour? *

Headache (pain in head): 20 people, 26.67%
Aggression: 19 people, 25.33%
Nausea And Vomiting: 15 people, 20.00%
Malaise (a feeling of general discomfort or uneasiness): 15 people, 20.00%
Dizziness: 13 people, 17.33%
Weakness: 12 people, 16.00%
Fall: 11 people, 14.67%
Gait Disturbance: 11 people, 14.67%
Drowsiness: 11 people, 14.67%
Joint Pain: 10 people, 13.33%

What are the existing conditions these people have? *

Insomnia (sleeplessness): 9 people, 12.00%
Vitamin B12 Decreased: 8 people, 10.67%
Encephalitis (inflammation of the brain): 8 people, 10.67%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 8 people, 10.67%
Blood Phosphorus Decreased: 8 people, 10.67%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 6 people, 8.00%
Acute Myeloid Leukaemia Recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent): 6 people, 8.00%
Pyogenic Liver Abscess (liver abscess caused by bacteria): 6 people, 8.00%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 6 people, 8.00%
Allergies: 6 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Acyclovir and have Abnormal behaviour?

- Check whether Abnormal behaviour is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acyclovir:

Acyclovir (54,961 reports)

Browse all side effects of Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Abnormal behaviour:

Abnormal behaviour (1,880 drugs)

Browse all the conditions that are associated with Abnormal behaviour:

Abnormal behaviour (2,156 conditions)

Drugs similar to Acyclovir and Abnormal behaviour :

Valtrex side effect: Abnormal behaviour

Related publications that referenced our studies

Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .

How the study uses the data?

The study uses data from the FDA. It is based on acyclovir (the active ingredients of Acyclovir) and Acyclovir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.