Acyclovir and Granulopenia - a phase IV clinical study of FDA data

Summary:

Granulopenia is reported as a side effect among people who take Acyclovir (acyclovir), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Dexamethasone, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Granulopenia when taking Acyclovir. It is created by eHealthMe based on reports of 53,484 people who have side effects when taking Acyclovir from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

What is Granulopenia?

Granulopenia (low white blood cell count) is found to be associated with 3,116 drugs and 3,549 conditions by eHealthMe. Check the latest studies of Granulopenia.

On Nov, 07, 2025

53,484 people reported to have side effects when taking Acyclovir.
Among them, 2,218 people (4.15%) have Granulopenia.

Among these 2,218 people:

How long have people been on Acyclovir when they have Granulopenia? *

What is the gender of people who have Granulopenia when taking Acyclovir? *

female: 49.21 %
male: 50.79 %

What is the age of people who have Granulopenia when taking Acyclovir? *

What are other drugs people take besides Acyclovir? *

What are other side effects people have besides Granulopenia? *

Thrombocytopenia (decrease of platelets in blood): 537 people, 24.21%
Fever: 419 people, 18.89%
Anaemia (lack of blood): 285 people, 12.85%
Diarrhea: 257 people, 11.59%
Nausea (feeling of having an urge to vomit): 246 people, 11.09%
Pneumonia: 233 people, 10.50%
Fatigue (feeling of tiredness): 228 people, 10.28%
Febrile Neutropenia (fever with reduced white blood cells): 212 people, 9.56%
Dyspnea (difficult or laboured breathing): 205 people, 9.24%
White Blood Cell Count Decreased: 156 people, 7.03%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 623 people, 28.09%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 182 people, 8.21%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 133 people, 6.00%
High Blood Pressure: 126 people, 5.68%
Nausea (feeling of having an urge to vomit): 119 people, 5.37%
Pain: 105 people, 4.73%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 87 people, 3.92%
Fever: 84 people, 3.79%
Constipation: 71 people, 3.20%
Bone Marrow Conditioning Regimen: 69 people, 3.11%

* Approximation only. Some reports may have incomplete information.

Do you take Acyclovir and have Granulopenia?

- Check whether Granulopenia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acyclovir:

Acyclovir (54,961 reports)

Granulopenia treatments and more:

Granulopenia (213,266 reports)

Browse all side effects of Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Granulopenia:

Browse all the drugs that are associated with Granulopenia:

Granulopenia (3,116 drugs)

Common conditions associated with Granulopenia:

Myeloma - multiple: 11,962 reports
Breast cancer: 6,926 reports
Cancer - breast: 6,849 reports
Breast cancer metastatic: 6,846 reports
Hypertension: 5,984 reports
Htn: 5,945 reports
Schizophrenia: 5,900 reports
Non-hodgkin's lymphoma: 4,423 reports
Diffuse large b-cell lymphoma: 4,399 reports
Cancer - non-hodgkin's lymphoma: 4,398 reports

Browse all the conditions that are associated with Granulopenia:

Granulopenia (3,549 conditions)

Drugs similar to Acyclovir and Granulopenia :

Valtrex side effect: Granulopenia

Related publications that referenced our studies

Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .

How the study uses the data?

The study uses data from the FDA. It is based on acyclovir (the active ingredients of Acyclovir) and Acyclovir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.