Acyclovir and Lower gastrointestinal haemorrhage - a phase IV clinical study of FDA data

Summary:

Lower gastrointestinal haemorrhage is reported as a side effect among people who take Acyclovir (acyclovir), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Ondansetron, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Lower gastrointestinal haemorrhage when taking Acyclovir. It is created by eHealthMe based on reports of 53,484 people who have side effects when taking Acyclovir from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

What is Lower gastrointestinal haemorrhage?

Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding) is found to be associated with 650 drugs and 582 conditions by eHealthMe. Check the latest studies of Lower gastrointestinal haemorrhage.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

53,484 people reported to have side effects when taking Acyclovir.
Among them, 29 people (0.05%) have Lower gastrointestinal haemorrhage.

Could Acyclovir cause Lower gastrointestinal haemorrhage?

Among these 29 people:

How long have people been on Acyclovir when they have Lower gastrointestinal haemorrhage? *

What is the gender of people who have Lower gastrointestinal haemorrhage when taking Acyclovir? *

female: 39.29 %
male: 60.71 %

What is the age of people who have Lower gastrointestinal haemorrhage when taking Acyclovir? *

What are other drugs people take besides Acyclovir? *

What are other side effects people have besides Lower gastrointestinal haemorrhage? *

Thrombocytopenia (decrease of platelets in blood): 12 people, 41.38%
Hypotension (abnormally low blood pressure): 9 people, 31.03%
Acute Kidney Failure: 9 people, 31.03%
General Physical Health Deterioration (weak health status): 7 people, 24.14%
Pneumonia: 6 people, 20.69%
Anaemia (lack of blood): 6 people, 20.69%
Confusional State: 6 people, 20.69%
Rectal Haemorrhage (bleeding from anus): 6 people, 20.69%
Diarrhea: 5 people, 17.24%
Coughing Up Blood: 5 people, 17.24%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 6 people, 20.69%
Bone Marrow Conditioning Regimen: 4 people, 13.79%
Pain: 3 people, 10.34%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 10.34%
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 2 people, 6.90%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 6.90%
Burkitt Lymphoma (cancer of the lymphatic system): 2 people, 6.90%
Chronic Graft Versus Host Disease (immune cells attack the host's body cells after transplant): 2 people, 6.90%
Hypertriglyceridaemia (excess of triglycerides in the blood): 2 people, 6.90%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

Do you take Acyclovir and have Lower gastrointestinal haemorrhage?

- Check whether Lower gastrointestinal haemorrhage is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acyclovir:

Acyclovir (54,961 reports)

Browse all side effects of Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lower gastrointestinal haemorrhage:

Lower gastrointestinal haemorrhage (650 drugs)

Browse all the conditions that are associated with Lower gastrointestinal haemorrhage:

Lower gastrointestinal haemorrhage (582 conditions)

Related publications that referenced our studies

Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .

How the study uses the data?

The study uses data from the FDA. It is based on acyclovir (the active ingredients of Acyclovir) and Acyclovir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.