Acyclovir and Microangiopathy - a phase IV clinical study of FDA data

Summary:

Microangiopathy is reported as a side effect among people who take Acyclovir (acyclovir), especially for people who are female, 10-19 old, have been taking the drug for 1 - 2 years also take Famotidine, and have Graft versus host disease.

The phase IV clinical study analyzes which people have Microangiopathy when taking Acyclovir. It is created by eHealthMe based on reports of 53,484 people who have side effects when taking Acyclovir from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

What is Microangiopathy?

Microangiopathy (disease of the capillaries (very small blood vessels), in which the capillary walls become so thick and weak that they bleed, leak protein) is found to be associated with 236 drugs and 331 conditions by eHealthMe. Check the latest studies of Microangiopathy.



On Jul, 15, 2026

53,484 people reported to have side effects when taking Acyclovir.
Among them, 15 people (0.03%) have Microangiopathy.

Could Acyclovir cause Microangiopathy?

Among these 15 people:

How long have people been on Acyclovir when they have Microangiopathy? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Microangiopathy when taking Acyclovir? *

  • female: 86.67 %
  • male: 13.33 %

What is the age of people who have Microangiopathy when taking Acyclovir? *

  • 0-1: 7.14 %
  • 2-9: 7.14 %
  • 10-19: 28.57 %
  • 20-29: 14.29 %
  • 30-39: 14.29 %
  • 40-49: 14.29 %
  • 50-59: 7.14 %
  • 60+: 7.14 %

What are other drugs people take besides Acyclovir? *

  1. Famotidine: 6 people, 40.00%
  2. Nexium: 5 people, 33.33%
  3. Methylprednisolone: 4 people, 26.67%
  4. Aranesp: 4 people, 26.67%
  5. Zosyn: 4 people, 26.67%
  6. Tacrolimus: 4 people, 26.67%
  7. Mycophenolate Mofetil: 4 people, 26.67%
  8. Exjade: 4 people, 26.67%
  9. Levothyroxine Sodium: 3 people, 20.00%
  10. Ursodiol: 3 people, 20.00%

What are other side effects people have besides Microangiopathy? *

  1. Bk Virus Infection: 4 people, 26.67%
  2. Concomitant Disease Aggravated (advanced due to some of accompanying): 4 people, 26.67%
  3. Clostridium Difficile Colitis (inflammation of colon by clostridium difficile bacteria infection): 4 people, 26.67%
  4. Nausea And Vomiting: 4 people, 26.67%
  5. Blood Creatinine Increased: 3 people, 20.00%
  6. Cerebral Ischaemia (insufficient blood flow to the brain to meet metabolic demand): 2 people, 13.33%
  7. Blood Phosphorus Increased: 2 people, 13.33%
  8. Blood Potassium Decreased: 2 people, 13.33%
  9. Blood Sodium Decreased: 2 people, 13.33%
  10. Blood Thyroid Stimulating Hormone Decreased: 2 people, 13.33%

What are the existing conditions these people have? *

  1. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 5 people, 33.33%
  2. Serum Ferritin Increased: 4 people, 26.67%
  3. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 4 people, 26.67%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 26.67%
  5. Anaemia (lack of blood): 4 people, 26.67%
  6. Multiple Myeloma (cancer of the plasma cells): 3 people, 20.00%
  7. High Blood Pressure: 3 people, 20.00%
  8. Immunodeficiency Disorders: 2 people, 13.33%
  9. Hiv Infection: 1 person, 6.67%
  10. Cytomegalovirus Infection: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Acyclovir and have Microangiopathy?

- Check whether Microangiopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acyclovir:

Microangiopathy treatments and more:

How severe was Microangiopathy and when was it recovered:

Expand to all the drugs that have ingredients of acyclovir:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Microangiopathy:

Browse all the conditions that are associated with Microangiopathy:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on acyclovir (the active ingredients of Acyclovir) and Acyclovir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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