Acyclovir and Monoparesis - a phase IV clinical study of FDA data

Summary:

Monoparesis is reported as a side effect among people who take Acyclovir (acyclovir), especially for people who are male, 60+ old, also take Ceftriaxone, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Monoparesis when taking Acyclovir. It is created by eHealthMe based on reports of 53,484 people who have side effects when taking Acyclovir from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

What is Monoparesis?

Monoparesis (one limb is very weak, but not completely paralyzed) is found to be associated with 315 drugs and 453 conditions by eHealthMe. Check the latest studies of Monoparesis.



On Aug, 12, 2026

53,484 people reported to have side effects when taking Acyclovir.
Among them, 17 people (0.03%) have Monoparesis.

Could Acyclovir cause Monoparesis?

Among these 17 people:

What is the gender of people who have Monoparesis when taking Acyclovir? *

  • female: 35.71 %
  • male: 64.29 %

What is the age of people who have Monoparesis when taking Acyclovir? *

  • 0-1: 0.0 %
  • 2-9: 20.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 26.67 %
  • 40-49: 6.67 %
  • 50-59: 6.67 %
  • 60+: 40.0 %

What are other drugs people take besides Acyclovir? *

  1. Dexamethasone: 6 people, 35.29%
  2. Ceftriaxone: 6 people, 35.29%
  3. Velcade: 4 people, 23.53%
  4. Methylprednisolone: 3 people, 17.65%
  5. Lorazepam: 2 people, 11.76%
  6. Azithromycin: 2 people, 11.76%
  7. Levofloxacin: 2 people, 11.76%
  8. Fentanyl: 1 person, 5.88%
  9. Levetiracetam: 1 person, 5.88%
  10. Lasix: 1 person, 5.88%

What are other side effects people have besides Monoparesis? *

  1. Speech Impairment (Adult) (inability to speak (adult)): 9 people, 52.94%
  2. Immune Reconstitution Syndrome (immune recovery syndrome): 4 people, 23.53%
  3. Visual Impairment: 4 people, 23.53%
  4. Fever: 4 people, 23.53%
  5. Drug Ineffective: 3 people, 17.65%
  6. Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 3 people, 17.65%
  7. Drowsiness: 3 people, 17.65%
  8. Depressed Level Of Consciousness: 3 people, 17.65%
  9. Weakness: 2 people, 11.76%
  10. Inflammation: 2 people, 11.76%

What are the existing conditions these people have? *

  1. Progressive Multifocal Leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells): 4 people, 23.53%
  2. Multiple Myeloma (cancer of the plasma cells): 4 people, 23.53%
  3. Upper Respiratory Tract Infection: 2 people, 11.76%
  4. Pneumonia: 2 people, 11.76%
  5. Meningitis Bacterial (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 2 people, 11.76%
  6. T-Cell Lymphoma Refractory (a t cell cancer resistant to treatment): 1 person, 5.88%
  7. Sedation: 1 person, 5.88%
  8. Primary Immunodeficiency Syndrome: 1 person, 5.88%
  9. Meningitis Eosinophilic (presence of more than 10 eosinophiles/mm3 in the cerebrospinal fluid): 1 person, 5.88%
  10. Intracranial Pressure Increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Acyclovir and have Monoparesis?

- Check whether Monoparesis is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acyclovir:

Monoparesis treatments and more:

How severe was Monoparesis and when was it recovered:

Expand to all the drugs that have ingredients of acyclovir:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Monoparesis:

Browse all the conditions that are associated with Monoparesis:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on acyclovir (the active ingredients of Acyclovir) and Acyclovir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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