Acyclovir and Muscle function loss - a phase IV clinical study of FDA data

Summary:

Muscle function loss is reported as a side effect among people who take Acyclovir (acyclovir), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Cyclophosphamide, and have Fluid retention.

The phase IV clinical study analyzes which people have Muscle function loss when taking Acyclovir. It is created by eHealthMe based on reports of 53,484 people who have side effects when taking Acyclovir from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

What is Muscle function loss?

Muscle function loss is found to be associated with 1,001 drugs and 1,521 conditions by eHealthMe. Check the latest studies of Muscle function loss.

On Jul, 17, 2026

53,484 people reported to have side effects when taking Acyclovir.
Among them, 48 people (0.09%) have Muscle function loss.

Could Acyclovir cause Muscle function loss?

Among these 48 people:

How long have people been on Acyclovir when they have Muscle function loss? *

What is the gender of people who have Muscle function loss when taking Acyclovir? *

female: 46.67 %
male: 53.33 %

What is the age of people who have Muscle function loss when taking Acyclovir? *

What are other drugs people take besides Acyclovir? *

What are other side effects people have besides Muscle function loss? *

Weakness: 18 people, 37.50%
Insomnia (sleeplessness): 14 people, 29.17%
Neuropathy Peripheral (surface nerve damage): 13 people, 27.08%
Pain: 13 people, 27.08%
Pneumonia: 12 people, 25.00%
Cough: 12 people, 25.00%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 10 people, 20.83%
Peripheral Swelling: 10 people, 20.83%
Dyspnea (difficult or laboured breathing): 10 people, 20.83%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 10 people, 20.83%

What are the existing conditions these people have? *

Prostate Cancer: 9 people, 18.75%
Multiple Myeloma (cancer of the plasma cells): 9 people, 18.75%
Nausea (feeling of having an urge to vomit): 9 people, 18.75%
Nausea And Vomiting: 9 people, 18.75%
Fluid Retention (an abnormal accumulation of fluid in the blood): 9 people, 18.75%
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 4 people, 8.33%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 8.33%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 6.25%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 6.25%
Temporal Lobe Epilepsy (a term that refers to a condition where seizures are generated in the portion of the brain called the temporal lobe): 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Acyclovir and have Muscle function loss?

- Check whether Muscle function loss is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acyclovir:

Acyclovir (54,961 reports)

Browse all side effects of Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle function loss:

Muscle function loss (1,001 drugs)

Browse all the conditions that are associated with Muscle function loss:

Muscle function loss (1,521 conditions)

Related publications that referenced our studies

Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .

How the study uses the data?

The study uses data from the FDA. It is based on acyclovir (the active ingredients of Acyclovir) and Acyclovir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.