Acyclovir and Nephrolithiasis - a phase IV clinical study of FDA data

Summary:

Nephrolithiasis is reported as a side effect among people who take Acyclovir (acyclovir), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Dexamethasone, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Nephrolithiasis when taking Acyclovir. It is created by eHealthMe based on reports of 53,484 people who have side effects when taking Acyclovir from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

What is Nephrolithiasis?

Nephrolithiasis (calculi in the kidneys) is found to be associated with 2,744 drugs and 2,118 conditions by eHealthMe. Check the latest studies of Nephrolithiasis.

On Jan, 12, 2026

53,484 people reported to have side effects when taking Acyclovir.
Among them, 238 people (0.44%) have Nephrolithiasis.

Among these 238 people:

* Approximation only. Some reports may have incomplete information.

Do you take Acyclovir and have Nephrolithiasis?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acyclovir:

Acyclovir (54,961 reports)

Nephrolithiasis treatments and more:

Nephrolithiasis (59,723 reports)

How severe was Nephrolithiasis and when was it recovered:

Nephrolithiasis in Acyclovir

Expand to all the drugs that have ingredients of acyclovir:

Nephrolithiasis and drugs with ingredients of acyclovir (255 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Acyclovir side effects:

Acyclovir side effect: Dyspnea (difficult or laboured breathing) (2,317 reports)

Browse all side effects of Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Nephrolithiasis:

Browse all the drugs that are associated with Nephrolithiasis:

Nephrolithiasis (2,744 drugs)

Common conditions associated with Nephrolithiasis:

Rheumatoid arthritis: 5,402 reports
Multiple sclerosis: 3,968 reports
Granulomatous ileocolitis: 3,666 reports
Hypertension: 2,644 reports
Blood pressure increased: 2,638 reports
Osteoporosis: 2,125 reports
Psoriasis: 1,846 reports
Pain: 1,800 reports
Alternative medicine - pain relief: 1,790 reports
Gerds: 1,586 reports

Browse all the conditions that are associated with Nephrolithiasis:

Nephrolithiasis (2,118 conditions)

Drugs similar to Acyclovir and Nephrolithiasis :

Valtrex side effect: Nephrolithiasis

Related publications that referenced our studies

Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .

How the study uses the data?

The study uses data from the FDA. It is based on acyclovir (the active ingredients of Acyclovir) and Acyclovir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.