Acyclovir and Shock - a phase IV clinical study of FDA data

Summary:

Shock is reported as a side effect among people who take Acyclovir (acyclovir), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Methylprednisolone, and have Status epilepticus.

The phase IV clinical study analyzes which people have Shock when taking Acyclovir. It is created by eHealthMe based on reports of 53,484 people who have side effects when taking Acyclovir from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

What is Shock?

Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin) is found to be associated with 1,243 drugs and 1,752 conditions by eHealthMe. Check the latest studies of Shock.

On Jan, 18, 2026

53,484 people reported to have side effects when taking Acyclovir.
Among them, 113 people (0.21%) have Shock.

Among these 113 people:

* Approximation only. Some reports may have incomplete information.

Do you take Acyclovir and have Shock?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acyclovir:

Acyclovir (54,961 reports)

Shock treatments and more:

Shock (28,534 reports)

How severe was Shock and when was it recovered:

Shock in Acyclovir

Expand to all the drugs that have ingredients of acyclovir:

Shock and drugs with ingredients of acyclovir (69 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Acyclovir side effects:

Acyclovir side effect: Thrombocytopenia (decrease of platelets in blood) (3,437 reports)
Acyclovir side effect: Nausea (feeling of having an urge to vomit) (3,362 reports)

Browse all side effects of Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Shock:

Browse all the drugs that are associated with Shock:

Shock (1,243 drugs)

Common conditions associated with Shock:

Browse all the conditions that are associated with Shock:

Shock (1,752 conditions)

Drugs similar to Acyclovir and Shock :

Valtrex side effect: Shock

Related publications that referenced our studies

Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .

How the study uses the data?

The study uses data from the FDA. It is based on acyclovir (the active ingredients of Acyclovir) and Acyclovir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.