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Acyclovir and Underactive thyroid - a phase IV clinical study of FDA data

Summary:

Underactive thyroid is reported as a side effect among people who take Acyclovir (acyclovir), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Prednisone, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Underactive thyroid when taking Acyclovir. It is created by eHealthMe based on reports of 53,484 people who have side effects when taking Acyclovir from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,957 Acyclovir users. Check the latest studies of Acyclovir.

What is Underactive thyroid?

Underactive thyroid is found to be associated with 2,789 drugs and 2,603 conditions by eHealthMe. Check the latest studies of Underactive thyroid.

On Jul, 31, 2025

53,484 people reported to have side effects when taking Acyclovir.
Among them, 454 people (0.85%) have Underactive thyroid.

Could Acyclovir cause Underactive thyroid?

Among these 454 people:

How long have people been on Acyclovir when they have Underactive thyroid? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Underactive thyroid when taking Acyclovir? *

  • female: 81.25 %
  • male: 18.75 %

What is the age of people who have Underactive thyroid when taking Acyclovir? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.27 %
  • 20-29: 0.8 %
  • 30-39: 2.93 %
  • 40-49: 12.27 %
  • 50-59: 63.47 %
  • 60+: 20.27 %

What are other drugs people take besides Acyclovir? *

  1. Prednisone: 256 people, 56.39%
  2. Clonazepam: 236 people, 51.98%
  3. Ergocalciferol: 234 people, 51.54%
  4. Albuterol: 232 people, 51.10%
  5. Levothyroxine Sodium: 230 people, 50.66%
  6. Spironolactone: 230 people, 50.66%
  7. Liothyronine Sodium: 217 people, 47.80%
  8. Apixaban: 213 people, 46.92%
  9. Nasonex: 213 people, 46.92%
  10. Montelukast Sodium: 202 people, 44.49%

What are other side effects people have besides Underactive thyroid? *

  1. High Blood Pressure: 296 people, 65.20%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 294 people, 64.76%
  3. Dyspnea (difficult or laboured breathing): 273 people, 60.13%
  4. Asthma: 270 people, 59.47%
  5. Headache (pain in head): 269 people, 59.25%
  6. Sleep Disorder: 258 people, 56.83%
  7. Carpal Tunnel Syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 250 people, 55.07%
  8. Fibromyalgia (a long-term condition which causes pain all over the body): 249 people, 54.85%
  9. Sleep Apnea Syndrome: 241 people, 53.08%
  10. Burning Sensation: 236 people, 51.98%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 50 people, 11.01%
  2. Asthma: 44 people, 9.69%
  3. High Blood Pressure: 32 people, 7.05%
  4. High Blood Cholesterol: 31 people, 6.83%
  5. Fluid Retention (an abnormal accumulation of fluid in the blood): 24 people, 5.29%
  6. Diarrhea: 24 people, 5.29%
  7. Mood Swings (an extreme or rapid change in mood): 24 people, 5.29%
  8. Joint Pain: 24 people, 5.29%
  9. Seborrhoeic Dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp): 24 people, 5.29%
  10. Blood Triglycerides Decreased: 17 people, 3.74%

* Approximation only. Some reports may have incomplete information.

Do you take Acyclovir and have Underactive thyroid?

- Check whether Underactive thyroid is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acyclovir:

Underactive thyroid treatments and more:

How severe was Underactive thyroid and when was it recovered:

Expand to all the drugs that have ingredients of acyclovir:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Acyclovir side effects:

Browse all side effects of Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Underactive thyroid:

Browse all the drugs that are associated with Underactive thyroid:

Common conditions associated with Underactive thyroid:

Browse all the conditions that are associated with Underactive thyroid:

Drugs similar to Acyclovir and Underactive thyroid :

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on acyclovir (the active ingredients of Acyclovir) and Acyclovir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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