Adalat and Muscle contracture - a phase IV clinical study of FDA data

Summary:

Muscle contracture is reported as a side effect among people who take Adalat (nifedipine), especially for people who are male, 60+ old, also take Prednisolone, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Muscle contracture when taking Adalat. It is created by eHealthMe based on reports of 20,643 people who have side effects when taking Adalat from the FDA, and is updated regularly.

What is Adalat?

Adalat has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 20,940 Adalat users. Check the latest studies of Adalat.

What is Muscle contracture?

Muscle contracture (a permanent shortening of a muscle) is found to be associated with 328 drugs and 525 conditions by eHealthMe. Check the latest studies of Muscle contracture.

On Aug, 12, 2026

20,643 people reported to have side effects when taking Adalat.
Among them, 11 people (0.05%) have Muscle contracture.

Among these 11 people:

What is the gender of people who have Muscle contracture when taking Adalat? *

female: 9.09 %
male: 90.91 %

What is the age of people who have Muscle contracture when taking Adalat? *

What are other drugs people take besides Adalat? *

What are other side effects people have besides Muscle contracture? *

Skin Induration (an abnormally hard spot or area on the skin): 6 people, 54.55%
Consciousness - Decreased: 5 people, 45.45%
Communication Disorder (speech and language disorder): 5 people, 45.45%
Fever: 5 people, 45.45%
Encephalopathy (functioning of the brain is affected by some agent or condition): 5 people, 45.45%
Dyspnea Exertional: 5 people, 45.45%
Respiratory Distress (difficulty in breathing): 5 people, 45.45%
Respiratory Tract Infection: 5 people, 45.45%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 5 people, 45.45%
Interstitial Lung Disease: 5 people, 45.45%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 45.45%
Rash Pruritic (redness with itching): 3 people, 27.27%
Enlarged Prostate: 2 people, 18.18%
Diabetes: 2 people, 18.18%
Monoclonal Gammopathy: 1 person, 9.09%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 9.09%
Dyslipidaemia (abnormal amount of lipids): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Adalat and have Muscle contracture?

- Check whether Muscle contracture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Adalat:

Adalat (20,940 reports)

Browse all side effects of Adalat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle contracture:

Muscle contracture (328 drugs)

Browse all the conditions that are associated with Muscle contracture:

Muscle contracture (525 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nifedipine (the active ingredients of Adalat) and Adalat (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.