Adalat and Progressive multifocal leukoencephalopathy - a phase IV clinical study of FDA data

Summary:

Progressive multifocal leukoencephalopathy is reported as a side effect among people who take Adalat (nifedipine), especially for people who are male, 50-59 old, also take Lansoprazole, and have Polyarteritis nodosa.

The phase IV clinical study analyzes which people have Progressive multifocal leukoencephalopathy when taking Adalat. It is created by eHealthMe based on reports of 20,643 people who have side effects when taking Adalat from the FDA, and is updated regularly.

What is Adalat?

Adalat has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 20,940 Adalat users. Check the latest studies of Adalat.

What is Progressive multifocal leukoencephalopathy?

Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells) is found to be associated with 592 drugs and 921 conditions by eHealthMe. Check the latest studies of Progressive multifocal leukoencephalopathy.

On Jul, 09, 2026

20,643 people reported to have side effects when taking Adalat.
Among them, 21 people (0.1%) have Progressive multifocal leukoencephalopathy.

Could Adalat cause Progressive multifocal leukoencephalopathy?

Among these 21 people:

What is the gender of people who have Progressive multifocal leukoencephalopathy when taking Adalat? *

female: 30 %
male: 70 %

What is the age of people who have Progressive multifocal leukoencephalopathy when taking Adalat? *

What are other drugs people take besides Adalat? *

What are other side effects people have besides Progressive multifocal leukoencephalopathy? *

Weight Decreased: 5 people, 23.81%
Basal Cell Carcinoma (a skin cancer, it rarely metastasizes or kills): 5 people, 23.81%
Dyspnea (difficult or laboured breathing): 5 people, 23.81%
Infection: 5 people, 23.81%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 23.81%
Staphylococcal Infection (an infection with staphylococcus bacteria): 5 people, 23.81%
Balance Disorder: 5 people, 23.81%
Neuralgia (pain in one or more nerves): 5 people, 23.81%
Pain: 5 people, 23.81%
Bladder Cancer: 5 people, 23.81%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 6 people, 28.57%
Polyarteritis Nodosa (progressive disease of connective tissue): 6 people, 28.57%
Mixed Connective Tissue Disease (an autoimmune disease, in which the body's defence system attacks itself): 5 people, 23.81%
Cellulitis (infection under the skin): 3 people, 14.29%
Ill-Defined Disorder: 3 people, 14.29%
Pain: 2 people, 9.52%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 9.52%
Depression: 2 people, 9.52%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 4.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Adalat and have Progressive multifocal leukoencephalopathy?

- Check whether Progressive multifocal leukoencephalopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Adalat:

Adalat (20,940 reports)

Progressive multifocal leukoencephalopathy treatments and more:

Progressive multifocal leukoencephalopathy (13,731 reports)

How severe was Progressive multifocal leukoencephalopathy and when was it recovered:

Progressive multifocal leukoencephalopathy in Adalat

Expand to all the drugs that have ingredients of nifedipine:

Progressive multifocal leukoencephalopathy and drugs with ingredients of nifedipine (40 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Adalat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Progressive multifocal leukoencephalopathy:

Progressive multifocal leukoencephalopathy (592 drugs)

Browse all the conditions that are associated with Progressive multifocal leukoencephalopathy:

Progressive multifocal leukoencephalopathy (921 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nifedipine (the active ingredients of Adalat) and Adalat (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.