Adcetris and C. diff - a phase IV clinical study of FDA data

Summary:

C. diff is reported as a side effect among people who take Adcetris (brentuximab vedotin), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Cyclophosphamide, and have Hodgkin's lymphoma.

The phase IV clinical study analyzes which people have C. diff when taking Adcetris. It is created by eHealthMe based on reports of 5,133 people who have side effects when taking Adcetris from the FDA, and is updated regularly.

What is Adcetris?

Adcetris has active ingredients of brentuximab vedotin. eHealthMe is studying from 5,136 Adcetris users. Check the latest studies of Adcetris.

What is C. diff?

C. diff is found to be associated with 1,625 drugs and 1,768 conditions by eHealthMe. Check the latest studies of C. diff.

On Oct, 26, 2025

5,133 people reported to have side effects when taking Adcetris.
Among them, 14 people (0.27%) have C. diff.

Among these 14 people:

How long have people been on Adcetris when they have C. diff? *

What is the gender of people who have C. diff when taking Adcetris? *

female: 36.36 %
male: 63.64 %

What is the age of people who have C. diff when taking Adcetris? *

What are other drugs people take besides Adcetris? *

Prednisone: 2 people, 14.29%
Cyclophosphamide: 2 people, 14.29%
Imodium: 1 person, 7.14%
Bendamustine: 1 person, 7.14%

What are other side effects people have besides C. diff? *

Thrombocytopenia (decrease of platelets in blood): 6 people, 42.86%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 5 people, 35.71%
Pneumonia: 4 people, 28.57%
Blood Alkaline Phosphatase Increased: 4 people, 28.57%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 21.43%
Anaemia (lack of blood): 3 people, 21.43%
Sinusitis (inflammation of sinus): 3 people, 21.43%
Febrile Neutropenia (fever with reduced white blood cells): 3 people, 21.43%
Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 3 people, 21.43%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 2 people, 14.29%

What are the existing conditions these people have? *

Hodgkin's Lymphoma (cancer originating from white blood cells): 8 people, 57.14%
Anaplastic Large Cell Lymphoma T- And Null-Cell Types (t-cell or null-cell cancer, a type of blood cancer): 3 people, 21.43%
Hodgkin's Disease Mixed Cellularity Stage Unspecified (cancer originating from white blood cells- stage unspecified): 2 people, 14.29%
Diarrhea: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Adcetris and have C. diff?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Adcetris:

Adcetris (5,136 reports)

C. diff treatments and more:

C. diff (13,844 reports)

Browse all side effects of Adcetris:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with C. diff:

C. diff (1,625 drugs)

Browse all the conditions that are associated with C. diff:

C. diff (1,768 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on brentuximab vedotin (the active ingredients of Adcetris) and Adcetris (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.