Adcetris and Cholestasis - a phase IV clinical study of FDA data

Summary:

Cholestasis is reported as a side effect among people who take Adcetris (brentuximab vedotin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Augmentin, and have Hodgkin's lymphoma.

The phase IV clinical study analyzes which people have Cholestasis when taking Adcetris. It is created by eHealthMe based on reports of 5,133 people who have side effects when taking Adcetris from the FDA, and is updated regularly.

What is Adcetris?

Adcetris has active ingredients of brentuximab vedotin. eHealthMe is studying from 5,136 Adcetris users. Check the latest studies of Adcetris.

What is Cholestasis?

Cholestasis (a condition where bile cannot flow from the liver to the duodenum) is found to be associated with 1,032 drugs and 1,815 conditions by eHealthMe. Check the latest studies of Cholestasis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

5,133 people reported to have side effects when taking Adcetris.
Among them, 17 people (0.33%) have Cholestasis.

Among these 17 people:

How long have people been on Adcetris when they have Cholestasis? *

What is the gender of people who have Cholestasis when taking Adcetris? *

female: 46.67 %
male: 53.33 %

What is the age of people who have Cholestasis when taking Adcetris? *

What are other drugs people take besides Adcetris? *

Ifosfamide: 3 people, 17.65%
Etoposide: 3 people, 17.65%
Doxorubicin Hydrochloride: 3 people, 17.65%
Cyclophosphamide: 3 people, 17.65%
Carboplatin: 3 people, 17.65%
Augmentin: 3 people, 17.65%
Vinorelbine: 2 people, 11.76%
Navelbine: 2 people, 11.76%
Gemcitabine: 2 people, 11.76%
Doxil: 2 people, 11.76%

What are other side effects people have besides Cholestasis? *

Blood Bilirubin Increased: 4 people, 23.53%
Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 3 people, 17.65%
Drug-Induced Liver Injury (diseases of the liver that are caused by physician-prescribed medications): 3 people, 17.65%
Hepatocellular Injury (liver injury): 3 people, 17.65%
Febrile Bone Marrow Aplasia (bone marrow greatly decreases or stops production of blood cells): 3 people, 17.65%
Cytomegalovirus Chorioretinitis (infection of choroid and retina of the eye from virus): 2 people, 11.76%
Cytomegalovirus Infection: 2 people, 11.76%
Transaminases Increased: 2 people, 11.76%
Uveitis (inflammation of the uvea): 1 person, 5.88%
Gamma-Glutamyltransferase Increased: 1 person, 5.88%

What are the existing conditions these people have? *

Hodgkin's Lymphoma (cancer originating from white blood cells): 7 people, 41.18%
Lymphoma (cancer that begins in immune system cells): 4 people, 23.53%
Fever: 3 people, 17.65%
Anaplastic Large Cell Lymphoma T- And Null-Cell Types (t-cell or null-cell cancer, a type of blood cancer): 3 people, 17.65%
Peripheral T-Cell Lymphoma Unspecified (peripheral t-cell cancer unspecified): 1 person, 5.88%
Cytomegalovirus Infection: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Adcetris and have Cholestasis?

- Check whether Cholestasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Adcetris:

Adcetris (5,136 reports)

Cholestasis treatments and more:

Cholestasis (23,731 reports)

Browse all side effects of Adcetris:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cholestasis:

Cholestasis (1,032 drugs)

Browse all the conditions that are associated with Cholestasis:

Cholestasis (1,815 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on brentuximab vedotin (the active ingredients of Adcetris) and Adcetris (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.