Adcirca and Sluggishness - a phase IV clinical study of FDA data

Summary:

Sluggishness is reported as a side effect among people who take Adcirca (tadalafil), especially for people who are female, 60+ old, also take Opsumit, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Sluggishness when taking Adcirca. It is created by eHealthMe based on reports of 54,899 people who have side effects when taking Adcirca from the FDA, and is updated regularly.

What is Adcirca?

Adcirca has active ingredients of tadalafil. It is often used in pulmonary hypertension. eHealthMe is studying from 54,957 Adcirca users. Check the latest studies of Adcirca.

What is Sluggishness?

Sluggishness (lacking alertness) is found to be associated with 869 drugs and 740 conditions by eHealthMe. Check the latest studies of Sluggishness.

On Jan, 10, 2026

54,899 people reported to have side effects when taking Adcirca.
Among them, 83 people (0.15%) have Sluggishness.

Among these 83 people:

* Approximation only. Some reports may have incomplete information.

Do you take Adcirca and have Sluggishness?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Adcirca:

Adcirca (54,957 reports)

Sluggishness treatments and more:

Sluggishness (11,737 reports)

How severe was Sluggishness and when was it recovered:

Sluggishness in Adcirca

Expand to all the drugs that have ingredients of tadalafil:

Sluggishness and drugs with ingredients of tadalafil (53 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Adcirca side effects:

Adcirca side effect: Nausea (feeling of having an urge to vomit) (5,267 reports)
Adcirca side effect: Malaise (a feeling of general discomfort or uneasiness) (3,426 reports)

Browse all side effects of Adcirca:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Sluggishness:

Browse all the drugs that are associated with Sluggishness:

Sluggishness (870 drugs)

Common conditions associated with Sluggishness:

Ms hug: 926 reports
Hypertension: 459 reports
High blood pressure: 458 reports
Depression: 395 reports
Rheumatoid arthritis: 391 reports
High blood cholesterol: 345 reports
Parkinson's disease: 298 reports
Pain: 296 reports
Anxiety: 282 reports
Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension: 281 reports

Browse all the conditions that are associated with Sluggishness:

Sluggishness (740 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tadalafil (the active ingredients of Adcirca) and Adcirca (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.