Aduhelm and Confusional state - a phase IV clinical study of FDA data

Summary:

Confusional state is reported as a side effect among people who take Aduhelm (aducanumab-avwa), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Donepezil Hydrochloride, and have Dementia alzheimer's type.

The phase IV clinical study analyzes which people have Confusional state when taking Aduhelm. It is created by eHealthMe based on reports of 520 people who have side effects when taking Aduhelm from the FDA, and is updated regularly.

What is Aduhelm?

Aduhelm has active ingredients of aducanumab-avwa. eHealthMe is studying from 520 Aduhelm users. Check the latest studies of Aduhelm.

What is Confusional state?

Confusional state is found to be associated with 2,721 drugs and 3,320 conditions by eHealthMe. Check the latest studies of Confusional state.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

520 people reported to have side effects when taking Aduhelm.
Among them, 49 people (9.42%) have Confusional state.

Among these 49 people:

How long have people been on Aduhelm when they have Confusional state? *

What is the gender of people who have Confusional state when taking Aduhelm? *

female: 46.94 %
male: 53.06 %

What is the age of people who have Confusional state when taking Aduhelm? *

What are other drugs people take besides Aduhelm? *

Donepezil Hydrochloride: 17 people, 34.69%
Vitamin D3: 14 people, 28.57%
Memantine: 12 people, 24.49%
Donepezil: 10 people, 20.41%
Coenzyme Q10: 9 people, 18.37%
Aspirin: 8 people, 16.33%
Lisinopril: 7 people, 14.29%
Aricept: 7 people, 14.29%
Vitamin B12: 7 people, 14.29%
Memantine Hydrochloride: 7 people, 14.29%

What are other side effects people have besides Confusional state? *

Headache (pain in head): 8 people, 16.33%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 7 people, 14.29%
Fatigue (feeling of tiredness): 7 people, 14.29%
Balance Disorder: 7 people, 14.29%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 6 people, 12.24%
Gait Disturbance: 6 people, 12.24%
Memory Loss: 6 people, 12.24%
Drowsiness: 6 people, 12.24%
Spinal Stenosis (narrowing of spinal column): 5 people, 10.20%
Facet Joint Syndrome (problem with movement of the facet joints of the spine): 5 people, 10.20%

What are the existing conditions these people have? *

Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 45 people, 91.84%
Oropharyngeal Pain: 2 people, 4.08%
Insomnia (sleeplessness): 2 people, 4.08%
Agitation (state of anxiety or nervous excitement): 2 people, 4.08%
Migraine (headache): 1 person, 2.04%
Delirium (wild excitement): 1 person, 2.04%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 1 person, 2.04%

* Approximation only. Some reports may have incomplete information.

Do you take Aduhelm and have Confusional state?

- Check whether Confusional state is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aduhelm:

Aduhelm (520 reports)

Confusional state treatments and more:

Confusional state (182,510 reports)

Browse all side effects of Aduhelm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Confusional state:

Confusional state (2,721 drugs)

Browse all the conditions that are associated with Confusional state:

Confusional state (3,320 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aducanumab-avwa (the active ingredients of Aduhelm) and Aduhelm (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.