Advair diskus 100/50 and Hypernatraemia - a phase IV clinical study of FDA data

Summary:

Hypernatraemia is reported as a side effect among people who take Advair diskus 100/50 (fluticasone propionate; salmeterol xinafoate), especially for people who are male, 50-59 old, have been taking the drug for 2 - 5 years also take Spiriva, and have Cardiac disorder.

The phase IV clinical study analyzes which people have Hypernatraemia when taking Advair diskus 100/50. It is created by eHealthMe based on reports of 38,800 people who have side effects when taking Advair diskus 100/50 from the FDA, and is updated regularly.

What is Advair diskus 100/50?

Advair diskus 100/50 has active ingredients of fluticasone propionate; salmeterol xinafoate. It is often used in asthma. eHealthMe is studying from 39,246 Advair diskus 100/50 users. Check the latest studies of Advair diskus 100/50.

What is Hypernatraemia?

Hypernatraemia (an abnormally high plasma concentration of sodium ions) is found to be associated with 654 drugs and 805 conditions by eHealthMe. Check the latest studies of Hypernatraemia.

On Jul, 04, 2026

38,800 people reported to have side effects when taking Advair diskus 100/50.
Among them, 13 people (0.03%) have Hypernatraemia.

Could Advair diskus 100/50 cause Hypernatraemia?

Among these 13 people:

How long have people been on Advair diskus 100/50 when they have Hypernatraemia? *

What is the gender of people who have Hypernatraemia when taking Advair diskus 100/50? *

female: 38.46 %
male: 61.54 %

What is the age of people who have Hypernatraemia when taking Advair diskus 100/50? *

What are other drugs people take besides Advair diskus 100/50? *

Spiriva: 9 people, 69.23%
Zosyn: 6 people, 46.15%
Sulfamethoxazole And Trimethoprim: 5 people, 38.46%
Albuterol: 5 people, 38.46%
Aspirin: 5 people, 38.46%
Digoxin: 4 people, 30.77%
Levaquin: 4 people, 30.77%
Mucinex: 4 people, 30.77%
Acetaminophen: 4 people, 30.77%
Vancomycin Hcl: 3 people, 23.08%

What are other side effects people have besides Hypernatraemia? *

Anaemia (lack of blood): 9 people, 69.23%
Breathing - Slowed Or Stopped: 7 people, 53.85%
Fever: 6 people, 46.15%
Cough: 6 people, 46.15%
Acute Kidney Failure: 5 people, 38.46%
Troponin Increased: 5 people, 38.46%
Dehydration (dryness resulting from the removal of water): 5 people, 38.46%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 5 people, 38.46%
Abdominal Distension: 4 people, 30.77%
Cardiac Failure Congestive: 4 people, 30.77%

What are the existing conditions these people have? *

Cardiac Disorder: 3 people, 23.08%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 15.38%
Heavy Or Prolong Menstrual Bleeding: 1 person, 7.69%
Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 7.69%
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 1 person, 7.69%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Advair diskus 100/50 and have Hypernatraemia?

- Check whether Hypernatraemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Advair diskus 100/50:

Advair diskus 100/50 (39,246 reports)

Hypernatraemia treatments and more:

Hypernatraemia (6,339 reports)

How severe was Hypernatraemia and when was it recovered:

Hypernatraemia in Advair diskus 100/50

Expand to all the drugs that have ingredients of fluticasone propionate; salmeterol xinafoate:

Hypernatraemia and drugs with ingredients of fluticasone propionate; salmeterol xinafoate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Advair diskus 100/50:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypernatraemia:

Hypernatraemia (654 drugs)

Browse all the conditions that are associated with Hypernatraemia:

Hypernatraemia (805 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fluticasone propionate; salmeterol xinafoate (the active ingredients of Advair diskus 100/50) and Advair diskus 100/50 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.