Advil cold and sinus and Feeling abnormal - a phase IV clinical study of FDA data

Summary:

Feeling abnormal is reported as a side effect among people who take Advil cold and sinus (ibuprofen; pseudoephedrine hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Nasonex, and have Headache.

The phase IV clinical study analyzes which people have Feeling abnormal when taking Advil cold and sinus. It is created by eHealthMe based on reports of 1,399 people who have side effects when taking Advil cold and sinus from the FDA, and is updated regularly.

What is Advil cold and sinus?

Advil cold and sinus has active ingredients of ibuprofen; pseudoephedrine hydrochloride. It is often used in sinus headache. eHealthMe is studying from 1,673 Advil cold and sinus users. Check the latest studies of Advil cold and sinus.

What is Feeling abnormal?

Feeling abnormal is found to be associated with 2,939 drugs and 3,341 conditions by eHealthMe. Check the latest studies of Feeling abnormal.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

1,399 people reported to have side effects when taking Advil cold and sinus.
Among them, 42 people (3.0%) have Feeling abnormal.

Could Advil cold and sinus cause Feeling abnormal?

Among these 42 people:

How long have people been on Advil cold and sinus when they have Feeling abnormal? *

What is the gender of people who have Feeling abnormal when taking Advil cold and sinus? *

female: 69.7 %
male: 30.3 %

What is the age of people who have Feeling abnormal when taking Advil cold and sinus? *

What are other drugs people take besides Advil cold and sinus? *

What are other side effects people have besides Feeling abnormal? *

Dizziness: 9 people, 21.43%
Nausea (feeling of having an urge to vomit): 9 people, 21.43%
Headache (pain in head): 6 people, 14.29%
Drug Ineffective: 6 people, 14.29%
Malaise (a feeling of general discomfort or uneasiness): 6 people, 14.29%
Drowsiness: 5 people, 11.90%
Diarrhea: 5 people, 11.90%
Fatigue (feeling of tiredness): 4 people, 9.52%
Cough: 4 people, 9.52%
Rhinorrhea (watery mucus discharge from the nose): 3 people, 7.14%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 9.52%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 9.52%
Nasopharyngitis (inflammation of the nasopharynx): 4 people, 9.52%
Headache (pain in head): 4 people, 9.52%
Hypersensitivity: 3 people, 7.14%
Stress And Anxiety: 2 people, 4.76%
Sinus Disorder (disease of sinus): 2 people, 4.76%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 4.76%
Paranasal Sinus Hypersecretion: 2 people, 4.76%
Tuberculin Test Positive: 2 people, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Advil cold and sinus and have Feeling abnormal?

- Check whether Feeling abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Advil cold and sinus:

Advil cold and sinus (1,673 reports)

Feeling abnormal treatments and more:

Feeling abnormal (276,628 reports)

How severe was Feeling abnormal and when was it recovered:

Feeling abnormal in Advil cold and sinus

Expand to all the drugs that have ingredients of ibuprofen; pseudoephedrine hydrochloride:

Feeling abnormal and drugs with ingredients of ibuprofen; pseudoephedrine hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Advil cold and sinus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Feeling abnormal:

Feeling abnormal (2,939 drugs)

Browse all the conditions that are associated with Feeling abnormal:

Feeling abnormal (3,341 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen; pseudoephedrine hydrochloride (the active ingredients of Advil cold and sinus) and Advil cold and sinus (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.