Advil and Jaw disorder - a phase IV clinical study of FDA data

Summary:

Jaw disorder is reported as a side effect among people who take Advil (ibuprofen), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zometa, and have Osteoporosis.

The phase IV clinical study analyzes which people have Jaw disorder when taking Advil. It is created by eHealthMe based on reports of 60,378 people who have side effects when taking Advil from the FDA, and is updated regularly.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,534 Advil users. Check the latest studies of Advil.

What is Jaw disorder?

Jaw disorder (jaw disease) is found to be associated with 747 drugs and 1,054 conditions by eHealthMe. Check the latest studies of Jaw disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

60,378 people reported to have side effects when taking Advil.
Among them, 54 people (0.09%) have Jaw disorder.

Among these 54 people:

How long have people been on Advil when they have Jaw disorder? *

What is the gender of people who have Jaw disorder when taking Advil? *

female: 92.45 %
male: 7.55 %

What is the age of people who have Jaw disorder when taking Advil? *

What are other drugs people take besides Advil? *

What are other side effects people have besides Jaw disorder? *

Tooth Disorder (tooth disease): 16 people, 29.63%
Bone Disorder: 15 people, 27.78%
Fatigue (feeling of tiredness): 14 people, 25.93%
Sinusitis (inflammation of sinus): 12 people, 22.22%
Osteonecrosis Of Jaw (death of bone of jaw): 12 people, 22.22%
Stress And Anxiety: 12 people, 22.22%
Toothaches (tooth pain): 11 people, 20.37%
Swelling Face: 11 people, 20.37%
Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 10 people, 18.52%
Back Pain: 10 people, 18.52%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 10 people, 18.52%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 11.11%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 7.41%
Birth Control: 3 people, 5.56%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 3 people, 5.56%
Neck Pain: 3 people, 5.56%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 5.56%
Stress And Anxiety: 3 people, 5.56%
Multiple Myeloma (cancer of the plasma cells): 3 people, 5.56%
Breast Cancer Metastatic: 2 people, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Advil and have Jaw disorder?

- Check whether Jaw disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Advil:

Advil (62,534 reports)

Jaw disorder treatments and more:

Jaw disorder (9,029 reports)

Browse all side effects of Advil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Jaw disorder:

Jaw disorder (747 drugs)

Browse all the conditions that are associated with Jaw disorder:

Jaw disorder (1,054 conditions)

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Advil) and Advil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.