Advil and Mitral valve prolapse - a phase IV clinical study of FDA data

Summary:

Mitral valve prolapse is reported as a side effect among people who take Advil (ibuprofen), especially for people who are female, 20-29 old, also take Nuvaring, and have Birth control.

The phase IV clinical study analyzes which people have Mitral valve prolapse when taking Advil. It is created by eHealthMe based on reports of 60,378 people who have side effects when taking Advil from the FDA, and is updated regularly.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,533 Advil users. Check the latest studies of Advil.

What is Mitral valve prolapse?

Mitral valve prolapse (heart's mitral valve doesn't work well) is found to be associated with 508 drugs and 859 conditions by eHealthMe. Check the latest studies of Mitral valve prolapse.

On Jul, 07, 2026

60,378 people reported to have side effects when taking Advil.
Among them, 23 people (0.04%) have Mitral valve prolapse.

Could Advil cause Mitral valve prolapse?

Among these 23 people:

What is the gender of people who have Mitral valve prolapse when taking Advil? *

female: 91.3 %
male: 8.7 %

What is the age of people who have Mitral valve prolapse when taking Advil? *

What are other drugs people take besides Advil? *

Nuvaring: 18 people, 78.26%
Cephalexin: 9 people, 39.13%
Diazepam: 9 people, 39.13%
Lortab: 6 people, 26.09%
Hydrocodone Bitartrate And Acetaminophen: 6 people, 26.09%
Adipex-P: 4 people, 17.39%
Lexapro: 3 people, 13.04%
Lamisil: 2 people, 8.70%
Tylenol: 2 people, 8.70%
Nexium: 2 people, 8.70%

What are other side effects people have besides Mitral valve prolapse? *

Hypotension (abnormally low blood pressure): 15 people, 65.22%
Pulmonary Embolism (blockage of the main artery of the lung): 15 people, 65.22%
Nausea (feeling of having an urge to vomit): 14 people, 60.87%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 13 people, 56.52%
Nausea And Vomiting: 13 people, 56.52%
Upper Respiratory Tract Infection: 12 people, 52.17%
Stress And Anxiety: 12 people, 52.17%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 11 people, 47.83%
Leukocytosis (increased white blood cells): 11 people, 47.83%
Injection Site Pain: 11 people, 47.83%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 13.04%
Birth Control: 3 people, 13.04%
Weight Loss: 2 people, 8.70%
Weight Decreased: 2 people, 8.70%
Pneumonia: 1 person, 4.35%
Neuralgia (pain in one or more nerves): 1 person, 4.35%
Muscle Rigidity (muscle stiffness): 1 person, 4.35%
Multiple Myeloma (cancer of the plasma cells): 1 person, 4.35%
Multiple Allergies (allergy to multiple agents): 1 person, 4.35%
Gait Disturbance: 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Advil and have Mitral valve prolapse?

- Check whether Mitral valve prolapse is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Advil:

Advil (62,533 reports)

Browse all side effects of Advil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mitral valve prolapse:

Mitral valve prolapse (508 drugs)

Browse all the conditions that are associated with Mitral valve prolapse:

Mitral valve prolapse (859 conditions)

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Advil) and Advil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.