Advil and Right ventricular failure - a phase IV clinical study of FDA data

Summary:

Right ventricular failure is reported as a side effect among people who take Advil (ibuprofen), especially for people who are female, 60+ old, also take Vitamin B12, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Right ventricular failure when taking Advil. It is created by eHealthMe based on reports of 60,378 people who have side effects when taking Advil from the FDA, and is updated regularly.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,533 Advil users. Check the latest studies of Advil.

What is Right ventricular failure?

Right ventricular failure (right half of the heart fails to work) is found to be associated with 590 drugs and 716 conditions by eHealthMe. Check the latest studies of Right ventricular failure.

On Jul, 12, 2026

60,378 people reported to have side effects when taking Advil.
Among them, 12 people (0.02%) have Right ventricular failure.

Could Advil cause Right ventricular failure?

Among these 12 people:

What is the gender of people who have Right ventricular failure when taking Advil? *

female: 83.33 %
male: 16.67 %

What is the age of people who have Right ventricular failure when taking Advil? *

What are other drugs people take besides Advil? *

What are other side effects people have besides Right ventricular failure? *

Oedema Peripheral (superficial swelling): 4 people, 33.33%
Dyspnea (difficult or laboured breathing): 4 people, 33.33%
Pericarditis (inflammation of the pericardium): 3 people, 25.00%
Pleural Effusion (water on the lungs): 3 people, 25.00%
Urine Output Decreased: 3 people, 25.00%
Pulmonary Embolism (blockage of the main artery of the lung): 3 people, 25.00%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 25.00%
Cardiotoxicity (damage to the heart muscle): 2 people, 16.67%
Chest Pain: 2 people, 16.67%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 16.67%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 33.33%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 25.00%
Prostatic Specific Antigen Increased: 2 people, 16.67%
Bone Cancer Metastatic: 2 people, 16.67%
Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 1 person, 8.33%
Stress And Anxiety: 1 person, 8.33%
Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 1 person, 8.33%
Prostate Cancer: 1 person, 8.33%
Polycystic Ovary Disease (cysts in the ovaries that occurs when the follicle stops developing): 1 person, 8.33%
Mantle Cell Lymphoma Stage Iv (cancer of lymphocytes, a type of white blood cell, spreads to other part of body): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Advil and have Right ventricular failure?

- Check whether Right ventricular failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Advil:

Advil (62,533 reports)

Browse all side effects of Advil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Right ventricular failure:

Right ventricular failure (590 drugs)

Browse all the conditions that are associated with Right ventricular failure:

Right ventricular failure (716 conditions)

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Advil) and Advil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.