Alcaine and Conjunctival hyperaemia - a phase IV clinical study of FDA data

Summary:

Conjunctival hyperaemia is reported as a side effect among people who take Alcaine (proparacaine hydrochloride), especially for people who are male, 30-39 old, also take Aredia, and have Macular oedema.

The phase IV clinical study analyzes which people have Conjunctival hyperaemia when taking Alcaine. It is created by eHealthMe based on reports of 329 people who have side effects when taking Alcaine from the FDA, and is updated regularly.

What is Alcaine?

Alcaine has active ingredients of proparacaine hydrochloride. eHealthMe is studying from 330 Alcaine users. Check the latest studies of Alcaine.

What is Conjunctival hyperaemia?

Conjunctival hyperaemia (congestion of conjunctival vessels) is found to be associated with 414 drugs and 620 conditions by eHealthMe. Check the latest studies of Conjunctival hyperaemia.

On Jul, 09, 2026

329 people reported to have side effects when taking Alcaine.
Among them, 52 people (15.81%) have Conjunctival hyperaemia.

Could Alcaine cause Conjunctival hyperaemia?

Among these 52 people:

What is the gender of people who have Conjunctival hyperaemia when taking Alcaine? *

female: 16.67 %
male: 83.33 %

What is the age of people who have Conjunctival hyperaemia when taking Alcaine? *

What are other drugs people take besides Alcaine? *

What are other side effects people have besides Conjunctival hyperaemia? *

Hypopyon (pus in the eye): 33 people, 63.46%
Eye Pain: 26 people, 50.00%
Corneal Epithelium Defect (outer layer defect of cornea): 24 people, 46.15%
Ulcerative Keratitis (ulcerative inflammation of the cornea): 23 people, 44.23%
Lacrimation Increased: 21 people, 40.38%
Photophobia (extreme sensitivity to light): 21 people, 40.38%
Corneal Oedema (corneal swelling): 19 people, 36.54%
Ciliary Hyperaemia (excessive accumulation of blood in a part of inside of eye tissue): 15 people, 28.85%
Keratopathy (noninflammatory disease of the cornea): 15 people, 28.85%
Vitritis (inflammation of the vitreous humour of the eye): 10 people, 19.23%

What are the existing conditions these people have? *

Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 12 people, 23.08%
Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 11 people, 21.15%
Eye Pain: 10 people, 19.23%
Eye Injury: 8 people, 15.38%
Foreign Body In Eye (foreign particle in eye): 7 people, 13.46%
Chemical Eye Injury: 3 people, 5.77%
Retinal Vessel Occlusion (a blockage in one of the small arteries): 2 people, 3.85%
Metastases To Bone (cancer spreads to bone): 1 person, 1.92%
Macular Degeneration (painless eye condition that leads to the gradual loss of central vision): 1 person, 1.92%
Age-Related Macular Degeneration: 1 person, 1.92%

* Approximation only. Some reports may have incomplete information.

Do you take Alcaine and have Conjunctival hyperaemia?

- Check whether Conjunctival hyperaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Alcaine:

Alcaine (330 reports)

Browse all side effects of Alcaine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Conjunctival hyperaemia:

Conjunctival hyperaemia (414 drugs)

Browse all the conditions that are associated with Conjunctival hyperaemia:

Conjunctival hyperaemia (620 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on proparacaine hydrochloride (the active ingredients of Alcaine) and Alcaine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.