Aldactone and Blood sodium abnormal - a phase IV clinical study of FDA data

Summary:

Blood sodium abnormal is reported as a side effect among people who take Aldactone (spironolactone), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Acute lymphocytic leukemia (all).

The phase IV clinical study analyzes which people have Blood sodium abnormal when taking Aldactone. It is created by eHealthMe based on reports of 45,404 people who have side effects when taking Aldactone from the FDA, and is updated regularly.

What is Aldactone?

Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 46,063 Aldactone users. Check the latest studies of Aldactone.

What is Blood sodium abnormal?

Blood sodium abnormal is found to be associated with 185 drugs and 243 conditions by eHealthMe. Check the latest studies of Blood sodium abnormal.

On Jul, 18, 2026

45,404 people reported to have side effects when taking Aldactone.
Among them, 12 people (0.03%) have Blood sodium abnormal.

Could Aldactone cause Blood sodium abnormal?

Among these 12 people:

How long have people been on Aldactone when they have Blood sodium abnormal? *

What is the gender of people who have Blood sodium abnormal when taking Aldactone? *

female: 75 %
male: 25 %

What is the age of people who have Blood sodium abnormal when taking Aldactone? *

What are other drugs people take besides Aldactone? *

What are other side effects people have besides Blood sodium abnormal? *

Gamma-Glutamyltransferase Increased: 3 people, 25.00%
Gallstones (stone formation by bile component): 3 people, 25.00%
Aspartate Aminotransferase Increased: 3 people, 25.00%
Blood Urea Abnormal: 3 people, 25.00%
Nausea (feeling of having an urge to vomit): 3 people, 25.00%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 25.00%
Blood Potassium Abnormal: 3 people, 25.00%
Alanine Aminotransferase Increased: 3 people, 25.00%
Diarrhea: 2 people, 16.67%
Hypotension (abnormally low blood pressure): 2 people, 16.67%

What are the existing conditions these people have? *

Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 25.00%
Gastric Ulcer (stomach ulcer): 3 people, 25.00%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 25.00%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 25.00%
Cardiac Failure: 3 people, 25.00%
Cerebral Infarction (less blood supply to brain resulting tissue damage): 3 people, 25.00%
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon): 3 people, 25.00%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 3 people, 25.00%
Insomnia (sleeplessness): 3 people, 25.00%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Aldactone and have Blood sodium abnormal?

- Check whether Blood sodium abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aldactone:

Aldactone (46,063 reports)

Browse all side effects of Aldactone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Blood sodium abnormal:

Blood sodium abnormal (185 drugs)

Browse all the conditions that are associated with Blood sodium abnormal:

Blood sodium abnormal (243 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on spironolactone (the active ingredients of Aldactone) and Aldactone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.