Aldactone and Enterobacter infection - a phase IV clinical study of FDA data

Summary:

Enterobacter infection is reported as a side effect among people who take Aldactone (spironolactone), especially for people who are male, 60+ old, also take Lasix, and have Pulmonary hypertension.

The phase IV clinical study analyzes which people have Enterobacter infection when taking Aldactone. It is created by eHealthMe based on reports of 45,404 people who have side effects when taking Aldactone from the FDA, and is updated regularly.

What is Aldactone?

Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 46,063 Aldactone users. Check the latest studies of Aldactone.

What is Enterobacter infection?

Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae) is found to be associated with 265 drugs and 554 conditions by eHealthMe. Check the latest studies of Enterobacter infection.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

45,404 people reported to have side effects when taking Aldactone.
Among them, 14 people (0.03%) have Enterobacter infection.

Could Aldactone cause Enterobacter infection?

Among these 14 people:

What is the gender of people who have Enterobacter infection when taking Aldactone? *

female: 46.15 %
male: 53.85 %

What is the age of people who have Enterobacter infection when taking Aldactone? *

What are other drugs people take besides Aldactone? *

What are other side effects people have besides Enterobacter infection? *

Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 28.57%
Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 4 people, 28.57%
Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries)): 3 people, 21.43%
Localised Infection (infection at the single location): 3 people, 21.43%
Aortic Aneurysm Rupture (enlarged aortic artery rapture caused by a weakening of the artery wall): 3 people, 21.43%
Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 3 people, 21.43%
Post Procedural Sepsis: 3 people, 21.43%
Right Ventricular Failure (right half of the heart fails to work): 2 people, 14.29%
Dermatitis Exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss): 2 people, 14.29%
Lactic Acidosis (low ph in body tissues): 2 people, 14.29%

What are the existing conditions these people have? *

Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 21.43%
Pituitary-Dependent Cushing's Syndrome (pituitary dependent hypercortisolism): 3 people, 21.43%
Dyslipidaemia (abnormal amount of lipids): 3 people, 21.43%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 21.43%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.14%
Lymphoedema (localized fluid retention and tissue swelling): 1 person, 7.14%
Adrenocortical Carcinoma (adrenal cortex cancer): 1 person, 7.14%
Flank Pain (a distressing sensation experienced around the lower back and the upper abdomen): 1 person, 7.14%
Hypoglycemia (low blood sugar): 1 person, 7.14%
Multiple Myeloma (cancer of the plasma cells): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Aldactone and have Enterobacter infection?

- Check whether Enterobacter infection is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aldactone:

Aldactone (46,063 reports)

Browse all side effects of Aldactone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Enterobacter infection:

Enterobacter infection (265 drugs)

Browse all the conditions that are associated with Enterobacter infection:

Enterobacter infection (554 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on spironolactone (the active ingredients of Aldactone) and Aldactone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.