Aldactone and Escherichia bacteraemia - a phase IV clinical study of FDA data

Summary:

Escherichia bacteraemia is reported as a side effect among people who take Aldactone (spironolactone), especially for people who are male, 60+ old, also take Lasix, and have Hepatitis c.

The phase IV clinical study analyzes which people have Escherichia bacteraemia when taking Aldactone. It is created by eHealthMe based on reports of 45,404 people who have side effects when taking Aldactone from the FDA, and is updated regularly.

What is Aldactone?

Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 46,063 Aldactone users. Check the latest studies of Aldactone.

What is Escherichia bacteraemia?

Escherichia bacteraemia (presence of bacteria escherichia coli in the blood) is found to be associated with 353 drugs and 487 conditions by eHealthMe. Check the latest studies of Escherichia bacteraemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

45,404 people reported to have side effects when taking Aldactone.
Among them, 13 people (0.03%) have Escherichia bacteraemia.

Could Aldactone cause Escherichia bacteraemia?

Among these 13 people:

What is the gender of people who have Escherichia bacteraemia when taking Aldactone? *

female: 23.08 %
male: 76.92 %

What is the age of people who have Escherichia bacteraemia when taking Aldactone? *

What are other drugs people take besides Aldactone? *

What are other side effects people have besides Escherichia bacteraemia? *

Peritonitis Bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial): 3 people, 23.08%
Thrombocytopenia (decrease of platelets in blood): 3 people, 23.08%
Gait Disturbance: 2 people, 15.38%
Hepatitis Cholestatic (flow of bile from the liver is slowed or blocked): 2 people, 15.38%
Dehydration (dryness resulting from the removal of water): 2 people, 15.38%
Dyspnea (difficult or laboured breathing): 2 people, 15.38%
Ascites (accumulation of fluid in the abdominal cavity): 2 people, 15.38%
Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 15.38%
Septic Shock (shock due to blood infection): 2 people, 15.38%
Acute Kidney Failure: 2 people, 15.38%

What are the existing conditions these people have? *

Hepatitis C: 3 people, 23.08%
Pain: 2 people, 15.38%
Ascites (accumulation of fluid in the abdominal cavity): 2 people, 15.38%
Type 2 Diabetes: 1 person, 7.69%
Thrombocytopenia (decrease of platelets in blood): 1 person, 7.69%
Systemic Mastocytosis (a condition caused by the accumulation of mast cells in more than one part of the body): 1 person, 7.69%
Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 7.69%
Peripheral T-Cell Lymphoma Unspecified Stage Iii (peripheral t-cell cancer unspecified stage iii): 1 person, 7.69%
Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 1 person, 7.69%
Blast Cell Count Decreased: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Aldactone and have Escherichia bacteraemia?

- Check whether Escherichia bacteraemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aldactone:

Aldactone (46,063 reports)

Browse all side effects of Aldactone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Escherichia bacteraemia:

Escherichia bacteraemia (353 drugs)

Browse all the conditions that are associated with Escherichia bacteraemia:

Escherichia bacteraemia (487 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on spironolactone (the active ingredients of Aldactone) and Aldactone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.