Aldactone and Extrasystoles - a phase IV clinical study of FDA data

Summary:

Extrasystoles is reported as a side effect among people who take Aldactone (spironolactone), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Lasix, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Extrasystoles when taking Aldactone. It is created by eHealthMe based on reports of 45,404 people who have side effects when taking Aldactone from the FDA, and is updated regularly.

What is Aldactone?

Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 46,063 Aldactone users. Check the latest studies of Aldactone.

What is Extrasystoles?

Extrasystoles is found to be associated with 745 drugs and 952 conditions by eHealthMe. Check the latest studies of Extrasystoles.



On Jul, 11, 2026

45,404 people reported to have side effects when taking Aldactone.
Among them, 42 people (0.09%) have Extrasystoles.

Could Aldactone cause Extrasystoles?

Among these 42 people:

How long have people been on Aldactone when they have Extrasystoles? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Extrasystoles when taking Aldactone? *

  • female: 62.5 %
  • male: 37.5 %

What is the age of people who have Extrasystoles when taking Aldactone? *

  • 0-1: 3.33 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 3.33 %
  • 30-39: 0.0 %
  • 40-49: 3.33 %
  • 50-59: 3.33 %
  • 60+: 86.67 %

What are other drugs people take besides Aldactone? *

  1. Lasix: 15 people, 35.71%
  2. Coumadin: 10 people, 23.81%
  3. Halcion: 7 people, 16.67%
  4. Aspirin: 6 people, 14.29%
  5. Digoxin: 6 people, 14.29%
  6. Effexor: 6 people, 14.29%
  7. Synthroid: 6 people, 14.29%
  8. Plavix: 5 people, 11.90%
  9. Coreg: 5 people, 11.90%
  10. Furosemide: 5 people, 11.90%

What are other side effects people have besides Extrasystoles? *

  1. Dyspnea (difficult or laboured breathing): 10 people, 23.81%
  2. Torsade De Pointes (a abnormal heart rate with abnormal beating pattern): 9 people, 21.43%
  3. Chest Pain: 8 people, 19.05%
  4. Fatigue (feeling of tiredness): 8 people, 19.05%
  5. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 8 people, 19.05%
  6. Electrocardiogram Qt Prolonged: 8 people, 19.05%
  7. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 16.67%
  8. Cardiac Failure Congestive: 6 people, 14.29%
  9. Nausea (feeling of having an urge to vomit): 6 people, 14.29%
  10. Stress And Anxiety: 6 people, 14.29%

What are the existing conditions these people have? *

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 9 people, 21.43%
  2. Cardiac Failure: 4 people, 9.52%
  3. Prostatitis (inflammation of the prostate gland): 3 people, 7.14%
  4. Otitis Externa (external ear infection): 3 people, 7.14%
  5. Diabetes: 3 people, 7.14%
  6. Urinary Tract Infection: 3 people, 7.14%
  7. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 4.76%
  8. Quit Smoking: 2 people, 4.76%
  9. Cardiac Disorder: 2 people, 4.76%
  10. Depression: 2 people, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Aldactone and have Extrasystoles?

- Check whether Extrasystoles is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aldactone:

Extrasystoles treatments and more:

How severe was Extrasystoles and when was it recovered:

Expand to all the drugs that have ingredients of spironolactone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Aldactone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Extrasystoles:

Browse all the conditions that are associated with Extrasystoles:


How the study uses the data?

The study uses data from the FDA. It is based on spironolactone (the active ingredients of Aldactone) and Aldactone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: