Aldactone and Joint dislocation - a phase IV clinical study of FDA data

Summary:

Joint dislocation is reported as a side effect among people who take Aldactone (spironolactone), especially for people who are female, 60+ old, also take Lasix, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Joint dislocation when taking Aldactone. It is created by eHealthMe based on reports of 45,404 people who have side effects when taking Aldactone from the FDA, and is updated regularly.

What is Aldactone?

Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 46,063 Aldactone users. Check the latest studies of Aldactone.

What is Joint dislocation?

Joint dislocation (a joint position is changed from normal position) is found to be associated with 1,008 drugs and 921 conditions by eHealthMe. Check the latest studies of Joint dislocation.

On Jul, 06, 2026

45,404 people reported to have side effects when taking Aldactone.
Among them, 35 people (0.08%) have Joint dislocation.

Could Aldactone cause Joint dislocation?

Among these 35 people:

What is the gender of people who have Joint dislocation when taking Aldactone? *

female: 88.57 %
male: 11.43 %

What is the age of people who have Joint dislocation when taking Aldactone? *

What are other drugs people take besides Aldactone? *

What are other side effects people have besides Joint dislocation? *

Fall: 22 people, 62.86%
Pain: 10 people, 28.57%
Dizziness: 10 people, 28.57%
Osteoporosis (bones weak and more likely to break): 9 people, 25.71%
Stress And Anxiety: 9 people, 25.71%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 9 people, 25.71%
Headache (pain in head): 8 people, 22.86%
Hypotension (abnormally low blood pressure): 8 people, 22.86%
Chest Pain: 8 people, 22.86%
Cellulitis (infection under the skin): 7 people, 20.00%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 22.86%
Thyroid Diseases: 5 people, 14.29%
Sinusitis (inflammation of sinus): 5 people, 14.29%
Sleep Disorder: 5 people, 14.29%
Indigestion: 5 people, 14.29%
Joint Swelling: 5 people, 14.29%
Peripheral Swelling: 4 people, 11.43%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 8.57%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 5.71%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

Do you take Aldactone and have Joint dislocation?

- Check whether Joint dislocation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aldactone:

Aldactone (46,063 reports)

Browse all side effects of Aldactone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint dislocation:

Joint dislocation (1,008 drugs)

Browse all the conditions that are associated with Joint dislocation:

Joint dislocation (921 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on spironolactone (the active ingredients of Aldactone) and Aldactone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.