Aldactone and Metastatic neoplasm - a phase IV clinical study of FDA data

Summary:

Metastatic neoplasm is reported as a side effect among people who take Aldactone (spironolactone), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Remeron, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Metastatic neoplasm when taking Aldactone. It is created by eHealthMe based on reports of 45,404 people who have side effects when taking Aldactone from the FDA, and is updated regularly.

What is Aldactone?

Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 46,063 Aldactone users. Check the latest studies of Aldactone.

What is Metastatic neoplasm?

Metastatic neoplasm (spreadable cancer tumour) is found to be associated with 601 drugs and 516 conditions by eHealthMe. Check the latest studies of Metastatic neoplasm.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

45,404 people reported to have side effects when taking Aldactone.
Among them, 14 people (0.03%) have Metastatic neoplasm.

Could Aldactone cause Metastatic neoplasm?

Among these 14 people:

How long have people been on Aldactone when they have Metastatic neoplasm? *

What is the gender of people who have Metastatic neoplasm when taking Aldactone? *

female: 50 %
male: 50 %

What is the age of people who have Metastatic neoplasm when taking Aldactone? *

What are other drugs people take besides Aldactone? *

What are other side effects people have besides Metastatic neoplasm? *

Hypotension (abnormally low blood pressure): 5 people, 35.71%
Intestinal Obstruction: 3 people, 21.43%
Oedema Peripheral (superficial swelling): 3 people, 21.43%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 3 people, 21.43%
Mitral Valve Incompetence (inefficient heart valve): 2 people, 14.29%
Fall: 2 people, 14.29%
Monoplegia (a paralysis of a single limb): 2 people, 14.29%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 14.29%
Metastases To Bone (cancer spreads to bone): 2 people, 14.29%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 2 people, 14.29%

What are the existing conditions these people have? *

Stress And Anxiety: 3 people, 21.43%
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 2 people, 14.29%
Cardiac Failure Acute: 2 people, 14.29%
Cardiac Failure Congestive: 2 people, 14.29%
Cushing's Syndrome (obesity, a rounded face, increased fat): 2 people, 14.29%
Menopause (end of monthly cycles in women): 2 people, 14.29%
Hepatitis C: 1 person, 7.14%
Back Pain: 1 person, 7.14%
Blood Disorder: 1 person, 7.14%
Blood Pressure Abnormal: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Aldactone and have Metastatic neoplasm?

- Check whether Metastatic neoplasm is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aldactone:

Aldactone (46,063 reports)

Browse all side effects of Aldactone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Metastatic neoplasm:

Metastatic neoplasm (601 drugs)

Browse all the conditions that are associated with Metastatic neoplasm:

Metastatic neoplasm (516 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on spironolactone (the active ingredients of Aldactone) and Aldactone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.