Aldactone and Nephropathy toxic - a phase IV clinical study of FDA data

Summary:

Nephropathy toxic is reported as a side effect among people who take Aldactone (spironolactone), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Neoral, and have Cardiac failure.

The phase IV clinical study analyzes which people have Nephropathy toxic when taking Aldactone. It is created by eHealthMe based on reports of 45,404 people who have side effects when taking Aldactone from the FDA, and is updated regularly.

What is Aldactone?

Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 46,063 Aldactone users. Check the latest studies of Aldactone.

What is Nephropathy toxic?

Nephropathy toxic (damage to kidney due to toxins) is found to be associated with 596 drugs and 737 conditions by eHealthMe. Check the latest studies of Nephropathy toxic.

On Jul, 26, 2026

45,404 people reported to have side effects when taking Aldactone.
Among them, 20 people (0.04%) have Nephropathy toxic.

Could Aldactone cause Nephropathy toxic?

Among these 20 people:

How long have people been on Aldactone when they have Nephropathy toxic? *

What is the gender of people who have Nephropathy toxic when taking Aldactone? *

female: 65 %
male: 35 %

What is the age of people who have Nephropathy toxic when taking Aldactone? *

What are other drugs people take besides Aldactone? *

What are other side effects people have besides Nephropathy toxic? *

Acute Kidney Failure: 7 people, 35.00%
Hyperkalemia (damage to or disease of the kidney): 7 people, 35.00%
Blood Creatinine Increased: 6 people, 30.00%
Urinary Tract Infection: 4 people, 20.00%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 3 people, 15.00%
Nausea And Vomiting: 3 people, 15.00%
Anaemia (lack of blood): 3 people, 15.00%
Hypotension (abnormally low blood pressure): 3 people, 15.00%
Conduction Disorder (serious disorder of the heart not responses proper to impulses): 2 people, 10.00%
Malaise (a feeling of general discomfort or uneasiness): 2 people, 10.00%

What are the existing conditions these people have? *

Cardiac Failure: 4 people, 20.00%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 10.00%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 10.00%
Hepatitis C: 2 people, 10.00%
Cardiac Failure Acute: 2 people, 10.00%
Back Pain: 2 people, 10.00%
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 1 person, 5.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.00%
Nausea And Vomiting: 1 person, 5.00%
Nausea (feeling of having an urge to vomit): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Aldactone and have Nephropathy toxic?

- Check whether Nephropathy toxic is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aldactone:

Aldactone (46,063 reports)

Browse all side effects of Aldactone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nephropathy toxic:

Nephropathy toxic (596 drugs)

Browse all the conditions that are associated with Nephropathy toxic:

Nephropathy toxic (737 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on spironolactone (the active ingredients of Aldactone) and Aldactone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.