Aldactone and Regurgitation - a phase IV clinical study of FDA data

Summary:

Regurgitation is reported as a side effect among people who take Aldactone (spironolactone), especially for people who are female, 50-59 old, also take Lasix, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Regurgitation when taking Aldactone. It is created by eHealthMe based on reports of 45,404 people who have side effects when taking Aldactone from the FDA, and is updated regularly.

What is Aldactone?

Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 46,063 Aldactone users. Check the latest studies of Aldactone.

What is Regurgitation?

Regurgitation (expulsion of material) is found to be associated with 434 drugs and 618 conditions by eHealthMe. Check the latest studies of Regurgitation.

On Jul, 12, 2026

45,404 people reported to have side effects when taking Aldactone.
Among them, 13 people (0.03%) have Regurgitation.

Among these 13 people:

What is the gender of people who have Regurgitation when taking Aldactone? *

female: 83.33 %
male: 16.67 %

What is the age of people who have Regurgitation when taking Aldactone? *

What are other drugs people take besides Aldactone? *

What are other side effects people have besides Regurgitation? *

Fatigue (feeling of tiredness): 8 people, 61.54%
Abdominal Pain: 7 people, 53.85%
Cough: 6 people, 46.15%
Headache (pain in head): 6 people, 46.15%
Nausea (feeling of having an urge to vomit): 6 people, 46.15%
Weight Increased: 5 people, 38.46%
Anaemia (lack of blood): 5 people, 38.46%
Chest Pain: 5 people, 38.46%
Haematochezia (passage of stools containing blood): 5 people, 38.46%
Dyspnea (difficult or laboured breathing): 4 people, 30.77%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 46.15%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 15.38%
Arrhythmias (irregular heartbeat): 2 people, 15.38%
Staphylococcal Sepsis (blood infection by an infection with staphylococcus bacteria): 1 person, 7.69%
Pain: 1 person, 7.69%
Infection: 1 person, 7.69%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 7.69%
Cardiac Failure Congestive: 1 person, 7.69%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Aldactone and have Regurgitation?

- Check whether Regurgitation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aldactone:

Aldactone (46,063 reports)

Regurgitation treatments and more:

Regurgitation (3,942 reports)

Browse all side effects of Aldactone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Regurgitation:

Regurgitation (434 drugs)

Browse all the conditions that are associated with Regurgitation:

Regurgitation (618 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on spironolactone (the active ingredients of Aldactone) and Aldactone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.