Aldactone and Uveitis - a phase IV clinical study of FDA data

Summary:

Uveitis is reported as a side effect among people who take Aldactone (spironolactone), especially for people who are female, 60+ old, also take Celebrex, and have Crohn's disease.

The phase IV clinical study analyzes which people have Uveitis when taking Aldactone. It is created by eHealthMe based on reports of 45,404 people who have side effects when taking Aldactone from the FDA, and is updated regularly.

What is Aldactone?

Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 46,063 Aldactone users. Check the latest studies of Aldactone.

What is Uveitis?

Uveitis (inflammation of the uvea) is found to be associated with 830 drugs and 1,533 conditions by eHealthMe. Check the latest studies of Uveitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 19, 2026

45,404 people reported to have side effects when taking Aldactone.
Among them, 42 people (0.09%) have Uveitis.

Among these 42 people:

What is the gender of people who have Uveitis when taking Aldactone? *

female: 90.62 %
male: 9.38 %

What is the age of people who have Uveitis when taking Aldactone? *

What are other drugs people take besides Aldactone? *

What are other side effects people have besides Uveitis? *

Malaise (a feeling of general discomfort or uneasiness): 17 people, 40.48%
Joint Pain: 16 people, 38.10%
Cough: 15 people, 35.71%
Hypotension (abnormally low blood pressure): 14 people, 33.33%
Anorectal Abscess: 13 people, 30.95%
Fever: 11 people, 26.19%
Canker Sores (painful, open sore in the mouth): 10 people, 23.81%
Stress And Anxiety: 10 people, 23.81%
Erythema Nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below): 10 people, 23.81%
Pain: 10 people, 23.81%

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 14 people, 33.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 28.57%
Fluid Retention (an abnormal accumulation of fluid in the blood): 10 people, 23.81%
Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 6 people, 14.29%
Constipation: 6 people, 14.29%
Depression: 6 people, 14.29%
The Flu (the flu is caused by an influenza virus): 6 people, 14.29%
Cardiac Failure Congestive: 4 people, 9.52%
Pain: 3 people, 7.14%
Breast Cancer Metastatic: 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Aldactone and have Uveitis?

- Check whether Uveitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aldactone:

Aldactone (46,063 reports)

Uveitis treatments and more:

Uveitis (29,545 reports)

Browse all side effects of Aldactone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Uveitis:

Uveitis (830 drugs)

Browse all the conditions that are associated with Uveitis:

Uveitis (1,533 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on spironolactone (the active ingredients of Aldactone) and Aldactone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.