Aldara and Application site vesicles - a phase IV clinical study of FDA data

Summary:

Application site vesicles is reported as a side effect among people who take Aldara (imiquimod), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Picato, and have Condyloma acuminatum.

The phase IV clinical study analyzes which people have Application site vesicles when taking Aldara. It is created by eHealthMe based on reports of 2,478 people who have side effects when taking Aldara from the FDA, and is updated regularly.

What is Aldara?

Aldara has active ingredients of imiquimod. It is often used in genital warts. eHealthMe is studying from 2,554 Aldara users. Check the latest studies of Aldara.

What is Application site vesicles?

Application site vesicles (small bubble within a cell at application site) is found to be associated with 270 drugs and 573 conditions by eHealthMe. Check the latest studies of Application site vesicles.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

2,478 people reported to have side effects when taking Aldara.
Among them, 14 people (0.56%) have Application site vesicles.

Could Aldara cause Application site vesicles?

Among these 14 people:

How long have people been on Aldara when they have Application site vesicles? *

What is the gender of people who have Application site vesicles when taking Aldara? *

female: 78.57 %
male: 21.43 %

What is the age of people who have Application site vesicles when taking Aldara? *

What are other drugs people take besides Aldara? *

What are other side effects people have besides Application site vesicles? *

Application Site Pain: 8 people, 57.14%
Application Site Erythema (redness of the skin at application site): 8 people, 57.14%
Muscle Aches (muscle pain): 3 people, 21.43%
Rashes (redness): 3 people, 21.43%
Application Site Swelling: 3 people, 21.43%
Application Site Ulcer: 3 people, 21.43%
Influenza Like Illness: 3 people, 21.43%
Application Site Irritation: 3 people, 21.43%
Application Site Inflammation: 2 people, 14.29%
Application Site Dryness: 2 people, 14.29%

What are the existing conditions these people have? *

Precancerous Skin Lesion: 2 people, 14.29%
Insomnia (sleeplessness): 2 people, 14.29%
Condyloma Acuminatum (rough growth resembling a cauliflower or a solid blister at genitals): 2 people, 14.29%
Lip Disorder (disease of lip): 1 person, 7.14%
Anogenital Warts: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Aldara and have Application site vesicles?

- Check whether Application site vesicles is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aldara:

Aldara (2,554 reports)

Browse all side effects of Aldara:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Application site vesicles:

Application site vesicles (270 drugs)

Browse all the conditions that are associated with Application site vesicles:

Application site vesicles (573 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on imiquimod (the active ingredients of Aldara) and Aldara (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.