Aldurazyme and Blindness - a phase IV clinical study of FDA data
Summary:
Blindness is reported as a side effect among people who take Aldurazyme (laronidase), especially for people who are male, 2-9 old, have been taking the drug for 5 - 10 years also take Amlodipine, and have Cardiac disorder.
The phase IV clinical study analyzes which people have Blindness when taking Aldurazyme. It is created by eHealthMe based on reports of 4,346 people who have side effects when taking Aldurazyme from the FDA, and is updated regularly.
What is Aldurazyme?
Aldurazyme has active ingredients of laronidase. eHealthMe is studying from 4,347 Aldurazyme users. Check the latest studies of Aldurazyme.
What is Blindness?
Blindness is found to be associated with 1,508 drugs and 1,990 conditions by eHealthMe. Check the latest studies of Blindness.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
4,346 people reported to have side effects when taking Aldurazyme.
Among them, 54 people (1.24%) have Blindness.

Among these 54 people:
How long have people been on Aldurazyme when they have Blindness? *
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 80 %
- 10+ years: 20 %
What is the gender of people who have Blindness when taking Aldurazyme? *
- female: 36.73 %
- male: 63.27 %
What is the age of people who have Blindness when taking Aldurazyme? *
- 0-1: 0.0 %
- 2-9: 51.28 %
- 10-19: 25.64 %
- 20-29: 0.0 %
- 30-39: 10.26 %
- 40-49: 10.26 %
- 50-59: 2.56 %
- 60+: 0.0 %
What are other drugs people take besides Aldurazyme? *
- Carvedilol: 3 people, 5.56%
- Amlodipine: 3 people, 5.56%
- Vitamins: 1 person, 1.85%
- Symbicort: 1 person, 1.85%
- Latanoprost: 1 person, 1.85%
- Fluorometholone: 1 person, 1.85%
- Epinephrine: 1 person, 1.85%
- Brimonidine: 1 person, 1.85%
- Aspirin: 1 person, 1.85%
- Albuterol Sulfate: 1 person, 1.85%
What are other side effects people have besides Blindness? *
- Hydrocephalus (water on the brain): 8 people, 14.81%
- Hypoacusis (loss of hearing): 7 people, 12.96%
- Pneumonia: 6 people, 11.11%
- Dyspnea (difficult or laboured breathing): 6 people, 11.11%
- Weakness: 6 people, 11.11%
- Pain: 5 people, 9.26%
- Pulmonary Valve Stenosis (heart valve disorder in which outflow of blood from the right ventricle of the heart is obstructed at the level of the pulmonic valve): 4 people, 7.41%
- Drug Ineffective: 4 people, 7.41%
- Nasopharyngitis (inflammation of the nasopharynx): 4 people, 7.41%
- Sleep Apnea Syndrome: 4 people, 7.41%
What are the existing conditions these people have? *
- Intraocular Pressure Increased: 2 people, 3.70%
- Cardiac Disorder: 2 people, 3.70%
- Cardiomyopathy (weakening of the heart muscle): 1 person, 1.85%
* Approximation only. Some reports may have incomplete information.
Do you take Aldurazyme and have Blindness?
- Check whether Blindness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Aldurazyme:
- Aldurazyme (4,347 reports)
Blindness treatments and more:
- Blindness (45,948 reports)
How severe was Blindness and when was it recovered:
Expand to all the drugs that have ingredients of laronidase:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Aldurazyme:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Blindness:
- Blindness (1,508 drugs)
Browse all the conditions that are associated with Blindness:
- Blindness (1,990 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on laronidase (the active ingredients of Aldurazyme) and Aldurazyme (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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