Aldurazyme and Bronchospasm - a phase IV clinical study of FDA data
Summary:
Bronchospasm is reported as a side effect among people who take Aldurazyme (laronidase), especially for people who are male, 2-9 old, have been taking the drug for 1 - 6 months also take Benadryl,.
The phase IV clinical study analyzes which people have Bronchospasm when taking Aldurazyme. It is created by eHealthMe based on reports of 4,346 people who have side effects when taking Aldurazyme from the FDA, and is updated regularly.
What is Aldurazyme?
Aldurazyme has active ingredients of laronidase. eHealthMe is studying from 4,347 Aldurazyme users. Check the latest studies of Aldurazyme.
What is Bronchospasm?
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi) is found to be associated with 1,139 drugs and 1,097 conditions by eHealthMe. Check the latest studies of Bronchospasm.
4,346 people reported to have side effects when taking Aldurazyme.
Among them, 28 people (0.64%) have Bronchospasm.

Among these 28 people:
How long have people been on Aldurazyme when they have Bronchospasm? *
- < 1 month: 10 %
- 1 - 6 months: 30 %
- 6 - 12 months: 20 %
- 1 - 2 years: 20 %
- 2 - 5 years: 10 %
- 5 - 10 years: 10 %
- 10+ years: 0.0 %
What is the gender of people who have Bronchospasm when taking Aldurazyme? *
- female: 25 %
- male: 75 %
What is the age of people who have Bronchospasm when taking Aldurazyme? *
- 0-1: 0.0 %
- 2-9: 66.67 %
- 10-19: 18.52 %
- 20-29: 7.41 %
- 30-39: 3.7 %
- 40-49: 3.7 %
- 50-59: 0.0 %
- 60+: 0.0 %
What are other drugs people take besides Aldurazyme? *
- Benadryl: 3 people, 10.71%
- Ibuprofen: 2 people, 7.14%
- Heparin: 2 people, 7.14%
- Prednisolone: 2 people, 7.14%
- Furosemide: 2 people, 7.14%
- Atrovent: 1 person, 3.57%
- Azithromycin: 1 person, 3.57%
- Baclofen: 1 person, 3.57%
- Bactrim: 1 person, 3.57%
- Cyclosporine: 1 person, 3.57%
What are other side effects people have besides Bronchospasm? *
- Dyspnea (difficult or laboured breathing): 5 people, 17.86%
- Pneumonia: 5 people, 17.86%
- Arrhythmias (irregular heartbeat): 5 people, 17.86%
- Fever: 5 people, 17.86%
- Oxygen Saturation Decreased: 4 people, 14.29%
- Respiratory Distress (difficulty in breathing): 4 people, 14.29%
- Nausea And Vomiting: 3 people, 10.71%
- Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs): 3 people, 10.71%
- Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 3 people, 10.71%
- Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 3 people, 10.71%
* Approximation only. Some reports may have incomplete information.
Do you take Aldurazyme and have Bronchospasm?
- Check whether Bronchospasm is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Aldurazyme:
- Aldurazyme (4,347 reports)
Bronchospasm treatments and more:
- Bronchospasm (18,622 reports)
How severe was Bronchospasm and when was it recovered:
Expand to all the drugs that have ingredients of laronidase:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Aldurazyme:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Bronchospasm:
- Bronchospasm (1,139 drugs)
Browse all the conditions that are associated with Bronchospasm:
- Bronchospasm (1,097 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on laronidase (the active ingredients of Aldurazyme) and Aldurazyme (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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