Alendronate sodium and Initial insomnia - a phase IV clinical study of FDA data

Summary:

Initial insomnia is reported as a side effect among people who take Alendronate sodium (alendronate sodium), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Fosamax, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Initial insomnia when taking Alendronate sodium. It is created by eHealthMe based on reports of 42,896 people who have side effects when taking Alendronate sodium from the FDA, and is updated regularly.

What is Alendronate sodium?

Alendronate sodium has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 43,608 Alendronate sodium users. Check the latest studies of Alendronate sodium.

What is Initial insomnia?

Initial insomnia (feeling of inadequate or poor-quality sleep) is found to be associated with 713 drugs and 690 conditions by eHealthMe. Check the latest studies of Initial insomnia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

42,896 people reported to have side effects when taking Alendronate sodium.
Among them, 13 people (0.03%) have Initial insomnia.

Could Alendronate sodium cause Initial insomnia?

Among these 13 people:

How long have people been on Alendronate sodium when they have Initial insomnia? *

What is the gender of people who have Initial insomnia when taking Alendronate sodium? *

female: 91.67 %
male: 8.33 %

What is the age of people who have Initial insomnia when taking Alendronate sodium? *

What are other drugs people take besides Alendronate sodium? *

What are other side effects people have besides Initial insomnia? *

Fall: 7 people, 53.85%
Kidney Stones: 6 people, 46.15%
High Blood Pressure: 5 people, 38.46%
Fatigue (feeling of tiredness): 5 people, 38.46%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 5 people, 38.46%
Cough: 5 people, 38.46%
Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 30.77%
Dizziness: 4 people, 30.77%
Pneumonia: 4 people, 30.77%
Femur Fracture: 4 people, 30.77%

What are the existing conditions these people have? *

Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 3 people, 23.08%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 23.08%
Haematuria (presence of blood in urine): 2 people, 15.38%
Vitamin D Decreased: 1 person, 7.69%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 7.69%
Ovarian Cancer (cancer of ovary): 1 person, 7.69%
Neoplasm Malignant (cancer tumour): 1 person, 7.69%
Muscle Spasms (muscle contraction): 1 person, 7.69%
Muscle Aches (muscle pain): 1 person, 7.69%
Memory Loss: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Alendronate sodium and have Initial insomnia?

- Check whether Initial insomnia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Alendronate sodium:

Alendronate sodium (43,608 reports)

Initial insomnia treatments and more:

Initial insomnia (12,139 reports)

Browse all side effects of Alendronate sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Initial insomnia:

Initial insomnia (713 drugs)

Browse all the conditions that are associated with Initial insomnia:

Initial insomnia (690 conditions)

Related publications that referenced our studies

Stuckey BG, Sallie R, "Alendronate-induced unmasking or deterioration of coeliac disease: a case series", Osteoporosis International, 2015 Jan .
Lee WY, Sun LM, Lin MC, Liang JA, Chang SN, Sung FC, Muo CH, Kao CH, "A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study", PloS one, 2012 Dec .
Stuckey BG, Sallie R, "Alendronate-induced unmasking or deterioration of coeliac disease: a case series", Osteoporosis International, 2015 Jan .
Lee WY, Sun LM, Lin MC, Liang JA, Chang SN, Sung FC, Muo CH, Kao CH, "A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study", PloS one, 2012 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on alendronate sodium (the active ingredients of Alendronate sodium) and Alendronate sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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