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Alendronic acid and Muscle rigidity - a phase IV clinical study of FDA data

Summary:

Muscle rigidity is reported as a side effect among people who take Alendronic acid (alendronate sodium), especially for people who are female, 60+ old, also take Omeprazole, and have Parkinson's disease.

The phase IV clinical study analyzes which people have Muscle rigidity when taking Alendronic acid. It is created by eHealthMe based on reports of 18,142 people who have side effects when taking Alendronic acid from the FDA, and is updated regularly.

What is Alendronic acid?

Alendronic acid has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 18,408 Alendronic acid users. Check the latest studies of Alendronic acid.

What is Muscle rigidity?

Muscle rigidity (muscle stiffness) is found to be associated with 787 drugs and 1,035 conditions by eHealthMe. Check the latest studies of Muscle rigidity.

On Jul, 09, 2026

18,142 people reported to have side effects when taking Alendronic acid.
Among them, 19 people (0.1%) have Muscle rigidity.

Could Alendronic acid cause Muscle rigidity?

Among these 19 people:

What is the gender of people who have Muscle rigidity when taking Alendronic acid? *

  • female: 77.78 %
  • male: 22.22 %

What is the age of people who have Muscle rigidity when taking Alendronic acid? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 29.41 %
  • 60+: 70.59 %

What are other drugs people take besides Alendronic acid? *

  1. Vitamin B12: 6 people, 31.58%
  2. Symmetrel: 6 people, 31.58%
  3. Sinemet: 6 people, 31.58%
  4. Omeprazole: 6 people, 31.58%
  5. Finasteride: 4 people, 21.05%
  6. Piperacillin And Tazobactam: 3 people, 15.79%
  7. Midodrine Hydrochloride: 3 people, 15.79%
  8. Moviprep: 3 people, 15.79%
  9. Acetaminophen: 3 people, 15.79%
  10. Stalevo 100: 3 people, 15.79%

What are other side effects people have besides Muscle rigidity? *

  1. Mobility Decreased (ability to move is reduced): 12 people, 63.16%
  2. Weight Decreased: 11 people, 57.89%
  3. Dyskinesia (abnormality or impairment of voluntary movement): 11 people, 57.89%
  4. On And Off Phenomenon: 11 people, 57.89%
  5. Abnormal Dreams: 11 people, 57.89%
  6. Memory Loss: 11 people, 57.89%
  7. Abnormal Faeces (abnormal stool): 10 people, 52.63%
  8. Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 10 people, 52.63%
  9. Feeling Abnormal: 10 people, 52.63%
  10. Constipation: 8 people, 42.11%

What are the existing conditions these people have? *

  1. Parkinson's Disease: 15 people, 78.95%
  2. Migraine (headache): 6 people, 31.58%
  3. Muscle Spasms (muscle contraction): 2 people, 10.53%
  4. Basedow's Disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Alendronic acid and have Muscle rigidity?

- Check whether Muscle rigidity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Alendronic acid:

Muscle rigidity treatments and more:

How severe was Muscle rigidity and when was it recovered:

Expand to all the drugs that have ingredients of alendronate sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Alendronic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle rigidity:

Browse all the conditions that are associated with Muscle rigidity:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on alendronate sodium (the active ingredients of Alendronic acid) and Alendronic acid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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