Aleve and Activated partial thromboplastin time prolonged - a phase IV clinical study of FDA data

Summary:

Activated partial thromboplastin time prolonged is reported as a side effect among people who take Aleve (naproxen sodium), especially for people who are female, 50-59 old, also take Advil, and have Ulcerative colitis.

The phase IV clinical study analyzes which people have Activated partial thromboplastin time prolonged when taking Aleve. It is created by eHealthMe based on reports of 68,206 people who have side effects when taking Aleve from the FDA, and is updated regularly.

What is Aleve?

Aleve has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 70,279 Aleve users. Check the latest studies of Aleve.

What is Activated partial thromboplastin time prolonged?

Activated partial thromboplastin time prolonged is found to be associated with 761 drugs and 1,210 conditions by eHealthMe. Check the latest studies of Activated partial thromboplastin time prolonged.

On Jul, 21, 2026

68,206 people reported to have side effects when taking Aleve.
Among them, 17 people (0.02%) have Activated partial thromboplastin time prolonged.

Could Aleve cause Activated partial thromboplastin time prolonged?

Among these 17 people:

What is the gender of people who have Activated partial thromboplastin time prolonged when taking Aleve? *

female: 58.82 %
male: 41.18 %

What is the age of people who have Activated partial thromboplastin time prolonged when taking Aleve? *

What are other drugs people take besides Aleve? *

What are other side effects people have besides Activated partial thromboplastin time prolonged? *

Haemoglobin Decreased: 6 people, 35.29%
Haematocrit Decreased: 5 people, 29.41%
Platelet Count Increased: 5 people, 29.41%
Acute Kidney Failure: 4 people, 23.53%
International Normalised Ratio Increased: 4 people, 23.53%
Hyperhidrosis (abnormally increased sweating): 4 people, 23.53%
Monocyte Count Increased: 4 people, 23.53%
Neutrophil Count Increased (excess than normal number of neutrophil a type of blood cell): 4 people, 23.53%
Back Pain: 4 people, 23.53%
Blood Albumin Decreased: 4 people, 23.53%

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 4 people, 23.53%
Scrotal Pain: 2 people, 11.76%
Scrotal Infection (infection in scrotum area): 2 people, 11.76%
High Blood Pressure: 2 people, 11.76%
Type 1 Diabetes: 1 person, 5.88%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 1 person, 5.88%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.88%
Multiple Myeloma (cancer of the plasma cells): 1 person, 5.88%
Lung Cancer - Non-Small Cell (lung cancer): 1 person, 5.88%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Aleve and have Activated partial thromboplastin time prolonged?

- Check whether Activated partial thromboplastin time prolonged is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aleve:

Aleve (70,279 reports)

Activated partial thromboplastin time prolonged treatments and more:

Activated partial thromboplastin time prolonged (8,799 reports)

How severe was Activated partial thromboplastin time prolonged and when was it recovered:

Activated partial thromboplastin time prolonged in Aleve

Expand to all the drugs that have ingredients of naproxen sodium:

Activated partial thromboplastin time prolonged and drugs with ingredients of naproxen sodium (23 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Aleve:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Activated partial thromboplastin time prolonged:

Activated partial thromboplastin time prolonged (761 drugs)

Browse all the conditions that are associated with Activated partial thromboplastin time prolonged:

Activated partial thromboplastin time prolonged (1,210 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on naproxen sodium (the active ingredients of Aleve) and Aleve (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.