Aleve and Exercise tolerance decreased - a phase IV clinical study of FDA data

Summary:

Exercise tolerance decreased is reported as a side effect among people who take Aleve (naproxen sodium), especially for people who are female, 60+ old, also take Venclexta, and have Chronic lymphocytic leukaemia.

The phase IV clinical study analyzes which people have Exercise tolerance decreased when taking Aleve. It is created by eHealthMe based on reports of 68,206 people who have side effects when taking Aleve from the FDA, and is updated regularly.

What is Aleve?

Aleve has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 70,279 Aleve users. Check the latest studies of Aleve.

What is Exercise tolerance decreased?

Exercise tolerance decreased is found to be associated with 622 drugs and 727 conditions by eHealthMe. Check the latest studies of Exercise tolerance decreased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

68,206 people reported to have side effects when taking Aleve.
Among them, 14 people (0.02%) have Exercise tolerance decreased.

Could Aleve cause Exercise tolerance decreased?

Among these 14 people:

What is the gender of people who have Exercise tolerance decreased when taking Aleve? *

female: 57.14 %
male: 42.86 %

What is the age of people who have Exercise tolerance decreased when taking Aleve? *

What are other drugs people take besides Aleve? *

What are other side effects people have besides Exercise tolerance decreased? *

Dyspnea (difficult or laboured breathing): 8 people, 57.14%
Fatigue (feeling of tiredness): 5 people, 35.71%
Nausea (feeling of having an urge to vomit): 5 people, 35.71%
Joint Pain: 4 people, 28.57%
Heart Rate Decreased: 4 people, 28.57%
Drowsiness: 4 people, 28.57%
Dizziness: 4 people, 28.57%
Diplopia (double vision): 4 people, 28.57%
Heart Rate Increased: 4 people, 28.57%
Confusional State: 4 people, 28.57%

What are the existing conditions these people have? *

Rhinorrhea (watery mucus discharge from the nose): 4 people, 28.57%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 28.57%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 4 people, 28.57%
Blood Phosphorus Increased: 2 people, 14.29%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 14.29%
Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 14.29%
Nuclear Magnetic Resonance Imaging Brain: 2 people, 14.29%
Immune System Disorder: 1 person, 7.14%
High Blood Cholesterol: 1 person, 7.14%
Migraine (headache): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Aleve and have Exercise tolerance decreased?

- Check whether Exercise tolerance decreased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aleve:

Aleve (70,279 reports)

Browse all side effects of Aleve:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Exercise tolerance decreased:

Exercise tolerance decreased (622 drugs)

Browse all the conditions that are associated with Exercise tolerance decreased:

Exercise tolerance decreased (727 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on naproxen sodium (the active ingredients of Aleve) and Aleve (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.