Aleve and Gallbladder non-functioning - a phase IV clinical study of FDA data

Summary:

Gallbladder non-functioning is reported as a side effect among people who take Aleve (naproxen sodium), especially for people who are female, 20-29 old, also take Yaz, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Gallbladder non-functioning when taking Aleve. It is created by eHealthMe based on reports of 68,206 people who have side effects when taking Aleve from the FDA, and is updated regularly.

What is Aleve?

Aleve has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 70,279 Aleve users. Check the latest studies of Aleve.

What is Gallbladder non-functioning?

Gallbladder non-functioning is found to be associated with 116 drugs and 440 conditions by eHealthMe. Check the latest studies of Gallbladder non-functioning.

On May, 02, 2026

68,206 people reported to have side effects when taking Aleve.
Among them, 13 people (0.02%) have Gallbladder non-functioning.

Could Aleve cause Gallbladder non-functioning?

Among these 13 people:

What is the gender of people who have Gallbladder non-functioning when taking Aleve? *

female: 100 %
male: 0.0 %

What is the age of people who have Gallbladder non-functioning when taking Aleve? *

What are other drugs people take besides Aleve? *

What are other side effects people have besides Gallbladder non-functioning? *

Nausea (feeling of having an urge to vomit): 4 people, 30.77%
Abdominal Pain Upper: 3 people, 23.08%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 3 people, 23.08%
Gallbladder Pain: 3 people, 23.08%
Gallstones (stone formation by bile component): 3 people, 23.08%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 15.38%
Nausea And Vomiting: 2 people, 15.38%
Abdominal Pain: 2 people, 15.38%
Cholecystitis (infection of gallbladder): 2 people, 15.38%
Cholecystitis Chronic (long lasting infection of gallbladder): 2 people, 15.38%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 23.08%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 15.38%
Depression: 2 people, 15.38%
Birth Control: 2 people, 15.38%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 7.69%
Thyroid Diseases: 1 person, 7.69%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
Joint Pain: 1 person, 7.69%
Blood Pressure Abnormal: 1 person, 7.69%
Bipolar Disorder (mood disorder): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Aleve and have Gallbladder non-functioning?

- Check whether Gallbladder non-functioning is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aleve:

Aleve (70,279 reports)

Browse all side effects of Aleve:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gallbladder non-functioning:

Gallbladder non-functioning (116 drugs)

Browse all the conditions that are associated with Gallbladder non-functioning:

Gallbladder non-functioning (440 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on naproxen sodium (the active ingredients of Aleve) and Aleve (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.