Aleve and Hyperthyroidism - a phase IV clinical study of FDA data

Summary:

Hyperthyroidism is reported as a side effect among people who take Aleve (naproxen sodium), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Promacta, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Hyperthyroidism when taking Aleve. It is created by eHealthMe based on reports of 68,206 people who have side effects when taking Aleve from the FDA, and is updated regularly.

What is Aleve?

Aleve has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 70,279 Aleve users. Check the latest studies of Aleve.

What is Hyperthyroidism?

Hyperthyroidism (over activity of the thyroid gland) is found to be associated with 1,006 drugs and 1,435 conditions by eHealthMe. Check the latest studies of Hyperthyroidism.

On Apr, 21, 2026

68,206 people reported to have side effects when taking Aleve.
Among them, 19 people (0.03%) have Hyperthyroidism.

Among these 19 people:

How long have people been on Aleve when they have Hyperthyroidism? *

What is the gender of people who have Hyperthyroidism when taking Aleve? *

female: 83.33 %
male: 16.67 %

What is the age of people who have Hyperthyroidism when taking Aleve? *

What are other drugs people take besides Aleve? *

What are other side effects people have besides Hyperthyroidism? *

High Blood Pressure: 6 people, 31.58%
Nausea (feeling of having an urge to vomit): 5 people, 26.32%
Nausea And Vomiting: 5 people, 26.32%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 26.32%
Dyspnea (difficult or laboured breathing): 4 people, 21.05%
Platelet Count Abnormal: 3 people, 15.79%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 15.79%
Chest Pain: 3 people, 15.79%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 15.79%
Drug Ineffective: 3 people, 15.79%

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 21.05%
Thrombocytopenia (decrease of platelets in blood): 3 people, 15.79%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 15.79%
High Blood Pressure: 2 people, 10.53%
Colon Cancer Stage Iv: 2 people, 10.53%
Insomnia (sleeplessness): 2 people, 10.53%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 10.53%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 10.53%
Carpal Tunnel Syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 1 person, 5.26%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Aleve and have Hyperthyroidism?

- Check whether Hyperthyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aleve:

Aleve (70,279 reports)

Hyperthyroidism treatments and more:

Hyperthyroidism (26,831 reports)

Browse all side effects of Aleve:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperthyroidism:

Hyperthyroidism (1,006 drugs)

Browse all the conditions that are associated with Hyperthyroidism:

Hyperthyroidism (1,435 conditions)

Related publications that referenced our studies

Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .
Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on naproxen sodium (the active ingredients of Aleve) and Aleve (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.