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Aleve and Suicidal behavior - a phase IV clinical study of FDA data

Summary:

Suicidal behavior is reported as a side effect among people who take Aleve (naproxen sodium), especially for people who are male, 60+ old, also take Chantix, and have Bipolar disorder.

The phase IV clinical study analyzes which people have Suicidal behavior when taking Aleve. It is created by eHealthMe based on reports of 68,206 people who have side effects when taking Aleve from the FDA, and is updated regularly.

What is Aleve?

Aleve has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 70,279 Aleve users. Check the latest studies of Aleve.

What is Suicidal behavior?

Suicidal behavior is found to be associated with 290 drugs and 448 conditions by eHealthMe. Check the latest studies of Suicidal behavior.

On Jul, 07, 2026

68,206 people reported to have side effects when taking Aleve.
Among them, 21 people (0.03%) have Suicidal behavior.

Could Aleve cause Suicidal behavior?

Among these 21 people:

What is the gender of people who have Suicidal behavior when taking Aleve? *

  • female: 19.05 %
  • male: 80.95 %

What is the age of people who have Suicidal behavior when taking Aleve? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 10 %
  • 40-49: 10 %
  • 50-59: 0.0 %
  • 60+: 80 %

What are other drugs people take besides Aleve? *

  1. Chantix: 16 people, 76.19%
  2. Claritin: 14 people, 66.67%
  3. Thorazine: 14 people, 66.67%
  4. Vitamins: 9 people, 42.86%
  5. Lithium Carbonate: 9 people, 42.86%
  6. Clonazepam: 4 people, 19.05%
  7. Benadryl: 3 people, 14.29%
  8. Prozac: 3 people, 14.29%
  9. Asa: 1 person, 4.76%
  10. Biotin: 1 person, 4.76%

What are other side effects people have besides Suicidal behavior? *

  1. Aggression: 15 people, 71.43%
  2. Agitation (state of anxiety or nervous excitement): 14 people, 66.67%
  3. Depression: 7 people, 33.33%
  4. Anger: 5 people, 23.81%
  5. Road Traffic Accident: 3 people, 14.29%
  6. Weight Decreased: 2 people, 9.52%
  7. Nervousness: 2 people, 9.52%
  8. Feeling Abnormal: 2 people, 9.52%
  9. Irritability: 2 people, 9.52%
  10. Abnormal Behavior: 2 people, 9.52%

What are the existing conditions these people have? *

  1. Sinus Disorder (disease of sinus): 14 people, 66.67%
  2. Bipolar Disorder (mood disorder): 14 people, 66.67%
  3. Quit Smoking: 10 people, 47.62%
  4. Prostatic Disorder: 10 people, 47.62%
  5. Toothaches (tooth pain): 1 person, 4.76%
  6. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 4.76%
  7. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Aleve and have Suicidal behavior?

- Check whether Suicidal behavior is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aleve:

Suicidal behavior treatments and more:

How severe was Suicidal behavior and when was it recovered:

Expand to all the drugs that have ingredients of naproxen sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Aleve:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Suicidal behavior:

Browse all the conditions that are associated with Suicidal behavior:

How the study uses the data?

The study uses data from the FDA. It is based on naproxen sodium (the active ingredients of Aleve) and Aleve (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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