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Aleve and Ventricular dysfunction - a phase IV clinical study of FDA data

Summary:

Ventricular dysfunction is reported as a side effect among people who take Aleve (naproxen sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Tylenol, and have Constipation.

The phase IV clinical study analyzes which people have Ventricular dysfunction when taking Aleve. It is created by eHealthMe based on reports of 68,206 people who have side effects when taking Aleve from the FDA, and is updated regularly.

What is Aleve?

Aleve has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 70,276 Aleve users. Check the latest studies of Aleve.

What is Ventricular dysfunction?

Ventricular dysfunction (heart dysfunction) is found to be associated with 533 drugs and 549 conditions by eHealthMe. Check the latest studies of Ventricular dysfunction.

On Nov, 04, 2025

68,206 people reported to have side effects when taking Aleve.
Among them, 16 people (0.02%) have Ventricular dysfunction.

Could Aleve cause Ventricular dysfunction?

Among these 16 people:

How long have people been on Aleve when they have Ventricular dysfunction? *

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Ventricular dysfunction when taking Aleve? *

  • female: 18.75 %
  • male: 81.25 %

What is the age of people who have Ventricular dysfunction when taking Aleve? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 22.22 %
  • 60+: 77.78 %

What are other drugs people take besides Aleve? *

  1. Tylenol: 7 people, 43.75%
  2. Zithromax: 6 people, 37.50%
  3. Pepcid: 6 people, 37.50%
  4. Motrin: 6 people, 37.50%
  5. Digoxin: 6 people, 37.50%
  6. Chlorothiazide: 6 people, 37.50%
  7. Colace: 6 people, 37.50%
  8. Paxil: 6 people, 37.50%
  9. Vioxx: 3 people, 18.75%
  10. Lipitor: 2 people, 12.50%

What are other side effects people have besides Ventricular dysfunction? *

  1. Cardiac Failure Congestive: 8 people, 50.00%
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 8 people, 50.00%
  3. Hepatic Failure (liver failure): 7 people, 43.75%
  4. Unilateral Hydronephrosis (kidney stone that causes obstruction of the ureter): 7 people, 43.75%
  5. Tricuspid Valve Incompetence (inefficient heart valve): 7 people, 43.75%
  6. Cardiac Disorder: 7 people, 43.75%
  7. Ventricular Hypertrophy (enlargement of ventricles (lower chambers) in the heart): 6 people, 37.50%
  8. Persistent Foetal Circulation (baby's blood does not need to pass by the lungs): 6 people, 37.50%
  9. Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 6 people, 37.50%
  10. Lung Disorder (lung disease): 6 people, 37.50%

What are the existing conditions these people have? *

  1. Stress And Anxiety: 6 people, 37.50%
  2. Panic Disorder: 6 people, 37.50%
  3. Constipation: 6 people, 37.50%
  4. Birth Control: 3 people, 18.75%
  5. Chest Pain: 2 people, 12.50%
  6. Back Pain: 2 people, 12.50%
  7. Shoulder Pain: 1 person, 6.25%
  8. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.25%
  9. Osteoporosis (bones weak and more likely to break): 1 person, 6.25%
  10. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Aleve and have Ventricular dysfunction?

- Check whether Ventricular dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aleve:

Ventricular dysfunction treatments and more:

How severe was Ventricular dysfunction and when was it recovered:

Expand to all the drugs that have ingredients of naproxen sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Aleve:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ventricular dysfunction:

Browse all the conditions that are associated with Ventricular dysfunction:

Drugs similar to Aleve and Ventricular dysfunction :

How the study uses the data?

The study uses data from the FDA. It is based on naproxen sodium (the active ingredients of Aleve) and Aleve (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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