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Alli and Epilepsy aggravated - a phase IV clinical study of FDA data

Summary:

Epilepsy aggravated is reported as a side effect among people who take Alli (orlistat), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Lamotrigine, and have Insomnia.

The phase IV clinical study analyzes which people have Epilepsy aggravated when taking Alli. It is created by eHealthMe based on reports of 22,320 people who have side effects when taking Alli from the FDA, and is updated regularly.

What is Alli?

Alli has active ingredients of orlistat. It is often used in weight loss. eHealthMe is studying from 22,818 Alli users. Check the latest studies of Alli.

What is Epilepsy aggravated?

Epilepsy aggravated (serious common and diverse set of chronic neurological disorders characterized by seizures) is found to be associated with 1,069 drugs and 456 conditions by eHealthMe. Check the latest studies of Epilepsy aggravated.

On Jul, 13, 2026

22,320 people reported to have side effects when taking Alli.
Among them, 12 people (0.05%) have Epilepsy aggravated.

Could Alli cause Epilepsy aggravated?

Among these 12 people:

How long have people been on Alli when they have Epilepsy aggravated? *

  • < 1 month: 85.71 %
  • 1 - 6 months: 14.29 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Epilepsy aggravated when taking Alli? *

  • female: 75 %
  • male: 25 %

What is the age of people who have Epilepsy aggravated when taking Alli? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 11.11 %
  • 20-29: 22.22 %
  • 30-39: 55.56 %
  • 40-49: 11.11 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Alli? *

  1. Lamotrigine: 4 people, 33.33%
  2. Zolpidem: 2 people, 16.67%
  3. Seroquel: 1 person, 8.33%
  4. Lantus Solostar: 1 person, 8.33%
  5. Keppra: 1 person, 8.33%
  6. Depakene: 1 person, 8.33%

What are other side effects people have besides Epilepsy aggravated? *

  1. Fainting (loss of consciousness and postural tone): 4 people, 33.33%
  2. Abnormal Behavior: 2 people, 16.67%
  3. Aggression: 2 people, 16.67%
  4. Agitation (state of anxiety or nervous excitement): 2 people, 16.67%
  5. Partial Seizures (seizures which affect only a part of the brain at onset): 2 people, 16.67%
  6. Pain: 2 people, 16.67%
  7. Memory Loss: 2 people, 16.67%
  8. Fever: 1 person, 8.33%
  9. Autism Spectrum Disorder (developmental disabilities that can cause significant social, communication and behavioural challenges): 1 person, 8.33%
  10. Blood Glucose Increased: 1 person, 8.33%

What are the existing conditions these people have? *

  1. Weight Decreased: 2 people, 16.67%
  2. Insomnia (sleeplessness): 2 people, 16.67%
  3. Type 1 Diabetes: 1 person, 8.33%
  4. Sleep Disorder: 1 person, 8.33%
  5. Gastric Cancer (stomach cancer): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Alli and have Epilepsy aggravated?

- Check whether Epilepsy aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Alli:

  • Alli (22,818 reports)

Epilepsy aggravated treatments and more:

How severe was Epilepsy aggravated and when was it recovered:

Expand to all the drugs that have ingredients of orlistat:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Alli:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Epilepsy aggravated:

Browse all the conditions that are associated with Epilepsy aggravated:

How the study uses the data?

The study uses data from the FDA. It is based on orlistat (the active ingredients of Alli) and Alli (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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