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Alli and Faecal volume increased - a phase IV clinical study of FDA data

Summary:

Faecal volume increased is reported as a side effect among people who take Alli (orlistat), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Centrum, and have Weight decreased.

The phase IV clinical study analyzes which people have Faecal volume increased when taking Alli. It is created by eHealthMe based on reports of 22,320 people who have side effects when taking Alli from the FDA, and is updated regularly.

What is Alli?

Alli has active ingredients of orlistat. It is often used in weight loss. eHealthMe is studying from 22,818 Alli users. Check the latest studies of Alli.

What is Faecal volume increased?

Faecal volume increased is found to be associated with 68 drugs and 405 conditions by eHealthMe. Check the latest studies of Faecal volume increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

22,320 people reported to have side effects when taking Alli.
Among them, 11 people (0.05%) have Faecal volume increased.

Could Alli cause Faecal volume increased?

Among these 11 people:

How long have people been on Alli when they have Faecal volume increased? *

  • < 1 month: 60 %
  • 1 - 6 months: 40 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Faecal volume increased when taking Alli? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Faecal volume increased when taking Alli? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 14.29 %
  • 30-39: 14.29 %
  • 40-49: 28.57 %
  • 50-59: 42.86 %
  • 60+: 0.0 %

What are other drugs people take besides Alli? *

  1. Centrum: 1 person, 9.09%

What are other side effects people have besides Faecal volume increased? *

  1. Diarrhea: 9 people, 81.82%
  2. Rectal Discharge (discharge from rectum): 4 people, 36.36%
  3. Faeces Hard: 3 people, 27.27%
  4. Therapeutic Response Unexpected: 3 people, 27.27%
  5. Flatulence (flatus expelled through the anus): 3 people, 27.27%
  6. Nausea (feeling of having an urge to vomit): 3 people, 27.27%
  7. Groin Pain: 2 people, 18.18%
  8. Muscle Spasms (muscle contraction): 2 people, 18.18%
  9. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 2 people, 18.18%
  10. Faecal Incontinence (a lack of control over passing stool): 2 people, 18.18%

What are the existing conditions these people have? *

  1. Weight Decreased: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Alli and have Faecal volume increased?

- Check whether Faecal volume increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Alli:

  • Alli (22,818 reports)

Faecal volume increased treatments and more:

How severe was Faecal volume increased and when was it recovered:

Expand to all the drugs that have ingredients of orlistat:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Alli:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Faecal volume increased:

Browse all the conditions that are associated with Faecal volume increased:

How the study uses the data?

The study uses data from the FDA. It is based on orlistat (the active ingredients of Alli) and Alli (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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