Allopurinol and Bladder hypertrophy - a phase IV clinical study of FDA data

Summary:

Bladder hypertrophy is reported as a side effect among people who take Allopurinol (allopurinol), especially for people who are male, 40-49 old, also take Keppra, and have Chronic lymphocytic leukaemia.

The phase IV clinical study analyzes which people have Bladder hypertrophy when taking Allopurinol. It is created by eHealthMe based on reports of 188,106 people who have side effects when taking Allopurinol from the FDA, and is updated regularly.

What is Allopurinol?

Allopurinol has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,869 Allopurinol users. Check the latest studies of Allopurinol.

What is Bladder hypertrophy?

Bladder hypertrophy (bladder overgrowth- increase in cell size) is found to be associated with 102 drugs and 154 conditions by eHealthMe. Check the latest studies of Bladder hypertrophy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

188,106 people reported to have side effects when taking Allopurinol.
Among them, 20 people (0.01%) have Bladder hypertrophy.

Could Allopurinol cause Bladder hypertrophy?

Among these 20 people:

What is the gender of people who have Bladder hypertrophy when taking Allopurinol? *

female: 0.0 %
male: 100 %

What is the age of people who have Bladder hypertrophy when taking Allopurinol? *

What are other drugs people take besides Allopurinol? *

What are other side effects people have besides Bladder hypertrophy? *

Dehydration (dryness resulting from the removal of water): 16 people, 80.00%
Oedema Peripheral (superficial swelling): 11 people, 55.00%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 11 people, 55.00%
Back Pain: 11 people, 55.00%
Pain: 11 people, 55.00%
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 10 people, 50.00%
Enlarged Prostate: 10 people, 50.00%
Urge Incontinence (urinary incontinence): 9 people, 45.00%
Adjustment Disorder: 9 people, 45.00%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 9 people, 45.00%

What are the existing conditions these people have? *

Immunoglobulins Decreased: 9 people, 45.00%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 9 people, 45.00%
Drug-Induced Liver Injury (diseases of the liver that are caused by physician-prescribed medications): 9 people, 45.00%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 9 people, 45.00%
Psoriasis (immune-mediated disease that affects the skin): 4 people, 20.00%
T-Cell Prolymphocytic Leukaemia (a aggressive type of t cell cancer): 2 people, 10.00%
Primary Myelofibrosis (primary disorder of the bone marrow): 2 people, 10.00%
Fat Embolism (fat obstruction due to injury): 2 people, 10.00%
Insomnia (sleeplessness): 1 person, 5.00%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Allopurinol and have Bladder hypertrophy?

- Check whether Bladder hypertrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Allopurinol:

Allopurinol (190,869 reports)

Browse all side effects of Allopurinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bladder hypertrophy:

Bladder hypertrophy (102 drugs)

Browse all the conditions that are associated with Bladder hypertrophy:

Bladder hypertrophy (154 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Allopurinol) and Allopurinol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.