Allopurinol and Brain stem ischaemia - a phase IV clinical study of FDA data

Summary:

Brain stem ischaemia is reported as a side effect among people who take Allopurinol (allopurinol), especially for people who are male, 60+ old, also take Tamsulosin, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Brain stem ischaemia when taking Allopurinol. It is created by eHealthMe based on reports of 188,106 people who have side effects when taking Allopurinol from the FDA, and is updated regularly.

What is Allopurinol?

Allopurinol has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,868 Allopurinol users. Check the latest studies of Allopurinol.

What is Brain stem ischaemia?

Brain stem ischaemia (a condition in which there is insufficient blood flow to the brain to meet metabolic demand) is found to be associated with 35 drugs and 113 conditions by eHealthMe. Check the latest studies of Brain stem ischaemia.

On Jul, 16, 2026

188,106 people reported to have side effects when taking Allopurinol.
Among them, 12 people (0.01%) have Brain stem ischaemia.

Could Allopurinol cause Brain stem ischaemia?

Among these 12 people:

What is the gender of people who have Brain stem ischaemia when taking Allopurinol? *

female: 8.33 %
male: 91.67 %

What is the age of people who have Brain stem ischaemia when taking Allopurinol? *

What are other drugs people take besides Allopurinol? *

What are other side effects people have besides Brain stem ischaemia? *

General Physical Health Deterioration (weak health status): 5 people, 41.67%
Weight Increased: 4 people, 33.33%
Balance Disorder: 4 people, 33.33%
Disturbance In Attention: 4 people, 33.33%
Dizziness: 4 people, 33.33%
Fall: 4 people, 33.33%
Fatigue (feeling of tiredness): 4 people, 33.33%
Arteritis (inflammation of the walls of arteries): 2 people, 16.67%
Bradycardia (abnormally slow heart action): 2 people, 16.67%
Cardiac Failure: 2 people, 16.67%

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 25.00%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 16.67%
Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 2 people, 16.67%
Multiple Myeloma (cancer of the plasma cells): 1 person, 8.33%
High Blood Pressure: 1 person, 8.33%
Diabetes: 1 person, 8.33%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 8.33%
Cardiac Failure Chronic: 1 person, 8.33%
Cardiac Failure: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Allopurinol and have Brain stem ischaemia?

- Check whether Brain stem ischaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Allopurinol:

Allopurinol (190,868 reports)

Browse all side effects of Allopurinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Brain stem ischaemia:

Brain stem ischaemia (35 drugs)

Browse all the conditions that are associated with Brain stem ischaemia:

Brain stem ischaemia (113 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Allopurinol) and Allopurinol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.