Allopurinol and Hyperreflexia - a phase IV clinical study of FDA data

Summary:

Hyperreflexia is reported as a side effect among people who take Allopurinol (allopurinol), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Escitalopram, and have Depression.

The phase IV clinical study analyzes which people have Hyperreflexia when taking Allopurinol. It is created by eHealthMe based on reports of 188,106 people who have side effects when taking Allopurinol from the FDA, and is updated regularly.

What is Allopurinol?

Allopurinol has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,868 Allopurinol users. Check the latest studies of Allopurinol.

What is Hyperreflexia?

Hyperreflexia (overactive or over responsive reflexes) is found to be associated with 422 drugs and 651 conditions by eHealthMe. Check the latest studies of Hyperreflexia.

On Aug, 04, 2026

188,106 people reported to have side effects when taking Allopurinol.
Among them, 47 people (0.02%) have Hyperreflexia.

Among these 47 people:

How long have people been on Allopurinol when they have Hyperreflexia? *

What is the gender of people who have Hyperreflexia when taking Allopurinol? *

female: 55.56 %
male: 44.44 %

What is the age of people who have Hyperreflexia when taking Allopurinol? *

What are other drugs people take besides Allopurinol? *

What are other side effects people have besides Hyperreflexia? *

Weakness: 23 people, 48.94%
Cardiac Failure: 20 people, 42.55%
Pneumonia: 19 people, 40.43%
Hypoaesthesia (reduced sense of touch or sensation): 18 people, 38.30%
Pupillary Reflex Impaired: 17 people, 36.17%
Urinary Retention (the inability to completely or partially empty the bladder): 17 people, 36.17%
Amaurosis (partial or total blindness without visible change in the eye): 17 people, 36.17%
Thermohypoaesthesia (a reduced sense of touch or sensation, or a partial loss of sensitivity to sensory stimuli heat): 17 people, 36.17%
Sight Disability (difficulty to see): 17 people, 36.17%
Multimorbidity (co-occurrence of two or more chronic medical conditions in one person): 17 people, 36.17%

What are the existing conditions these people have? *

Depression: 20 people, 42.55%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 19 people, 40.43%
High Blood Pressure: 19 people, 40.43%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 18 people, 38.30%
Cardiac Failure Congestive: 17 people, 36.17%
Osteoporosis (bones weak and more likely to break): 17 people, 36.17%
Oesophagitis (inflammation of oesophagus): 17 people, 36.17%
Iron Deficiency: 17 people, 36.17%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 16 people, 34.04%
Acarodermatitis (skin inflammation caused by mites (acarids)): 2 people, 4.26%

* Approximation only. Some reports may have incomplete information.

Do you take Allopurinol and have Hyperreflexia?

- Check whether Hyperreflexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Allopurinol:

Allopurinol (190,868 reports)

Hyperreflexia treatments and more:

Hyperreflexia (4,677 reports)

Browse all side effects of Allopurinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperreflexia:

Hyperreflexia (422 drugs)

Browse all the conditions that are associated with Hyperreflexia:

Hyperreflexia (651 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Allopurinol) and Allopurinol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.