Allopurinol and Hypopituitarism - a phase IV clinical study of FDA data

Summary:

Hypopituitarism is reported as a side effect among people who take Allopurinol (allopurinol), especially for people who are male, 60+ old, also take Amlodipine, and have Lung cancer - non-small cell.

The phase IV clinical study analyzes which people have Hypopituitarism when taking Allopurinol. It is created by eHealthMe based on reports of 188,106 people who have side effects when taking Allopurinol from the FDA, and is updated regularly.

What is Allopurinol?

Allopurinol has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,868 Allopurinol users. Check the latest studies of Allopurinol.

What is Hypopituitarism?

Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults) is found to be associated with 202 drugs and 451 conditions by eHealthMe. Check the latest studies of Hypopituitarism.

On Jul, 27, 2026

188,106 people reported to have side effects when taking Allopurinol.
Among them, 22 people (0.01%) have Hypopituitarism.

Could Allopurinol cause Hypopituitarism?

Among these 22 people:

What is the gender of people who have Hypopituitarism when taking Allopurinol? *

female: 0.0 %
male: 100 %

What is the age of people who have Hypopituitarism when taking Allopurinol? *

What are other drugs people take besides Allopurinol? *

What are other side effects people have besides Hypopituitarism? *

Dementia With Lewy Bodies (progressive degenerative disease or syndrome of the brain): 5 people, 22.73%
Secondary Adrenocortical Insufficiency (inadequate secretion of acth by the pituitary gland): 5 people, 22.73%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 4 people, 18.18%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 4 people, 18.18%
Blood Creatinine Increased: 4 people, 18.18%
Confusional State: 4 people, 18.18%
Dehydration (dryness resulting from the removal of water): 4 people, 18.18%
Hypophysitis (inflammation of the pituitary gland): 4 people, 18.18%
Thyroid Diseases: 3 people, 13.64%
Adrenocortical Insufficiency Acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones): 3 people, 13.64%

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 7 people, 31.82%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 6 people, 27.27%
High Blood Pressure: 4 people, 18.18%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 4 people, 18.18%
Constipation: 3 people, 13.64%
Therapeutic Embolisation: 3 people, 13.64%
Type 2 Diabetes: 2 people, 9.09%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 2 people, 9.09%
Non-Small Cell Lung Cancer Recurrent (type of epithelial lung cancer reoccurrence): 2 people, 9.09%
Pancreatitis Chronic (chronic inflammation of pancreas): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Allopurinol and have Hypopituitarism?

- Check whether Hypopituitarism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Allopurinol:

Allopurinol (190,868 reports)

Hypopituitarism treatments and more:

Hypopituitarism (11,449 reports)

Browse all side effects of Allopurinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypopituitarism:

Hypopituitarism (202 drugs)

Browse all the conditions that are associated with Hypopituitarism:

Hypopituitarism (451 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Allopurinol) and Allopurinol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.