Allopurinol and Ocular icterus - a phase IV clinical study of FDA data
Summary:
Ocular icterus is reported as a side effect among people who take Allopurinol (allopurinol), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Lisinopril, and have High blood pressure.
The phase IV clinical study analyzes which people have Ocular icterus when taking Allopurinol. It is created by eHealthMe based on reports of 188,106 people who have side effects when taking Allopurinol from the FDA, and is updated regularly.
What is Allopurinol?
Allopurinol has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,869 Allopurinol users. Check the latest studies of Allopurinol.
What is Ocular icterus?
Ocular icterus (presence of jaundice seen in the sclera of the eye) is found to be associated with 503 drugs and 783 conditions by eHealthMe. Check the latest studies of Ocular icterus.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
188,106 people reported to have side effects when taking Allopurinol.
Among them, 61 people (0.03%) have Ocular icterus.

Among these 61 people:
How long have people been on Allopurinol when they have Ocular icterus? *
- < 1 month: 25 %
- 1 - 6 months: 25 %
- 6 - 12 months: 50 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Ocular icterus when taking Allopurinol? *
- female: 22.03 %
- male: 77.97 %
What is the age of people who have Ocular icterus when taking Allopurinol? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 10.87 %
- 20-29: 0.0 %
- 30-39: 6.52 %
- 40-49: 13.04 %
- 50-59: 28.26 %
- 60+: 41.3 %
What are other drugs people take besides Allopurinol? *
- Lisinopril: 23 people, 37.70%
- Aspirin: 20 people, 32.79%
- Protonix: 18 people, 29.51%
- Sutent: 18 people, 29.51%
- Lipitor: 16 people, 26.23%
- Lamisil: 15 people, 24.59%
- Nexavar: 15 people, 24.59%
- Megace: 15 people, 24.59%
- Sporanox: 15 people, 24.59%
- Synthroid: 15 people, 24.59%
What are other side effects people have besides Ocular icterus? *
- Pain: 30 people, 49.18%
- Stress And Anxiety: 27 people, 44.26%
- Quality Of Life Decreased: 25 people, 40.98%
- Joint Swelling: 21 people, 34.43%
- Rashes (redness): 20 people, 32.79%
- Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 18 people, 29.51%
- Abdominal Pain: 17 people, 27.87%
- Haematochezia (passage of stools containing blood): 17 people, 27.87%
- Fatigue (feeling of tiredness): 17 people, 27.87%
- Anaemia (lack of blood): 17 people, 27.87%
What are the existing conditions these people have? *
- Pain: 9 people, 14.75%
- High Blood Pressure: 9 people, 14.75%
- Blood Phosphorus Increased: 7 people, 11.48%
- Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 7 people, 11.48%
- Diabetes: 6 people, 9.84%
- Nuclear Magnetic Resonance Imaging Abdominal: 5 people, 8.20%
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 5 people, 8.20%
- Depression: 4 people, 6.56%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 6.56%
- Bleeding Disorders: 3 people, 4.92%
* Approximation only. Some reports may have incomplete information.
Do you take Allopurinol and have Ocular icterus?
- Check whether Ocular icterus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Allopurinol:
- Allopurinol (190,869 reports)
Ocular icterus treatments and more:
- Ocular icterus (5,127 reports)
How severe was Ocular icterus and when was it recovered:
Expand to all the drugs that have ingredients of allopurinol:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Allopurinol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Ocular icterus:
- Ocular icterus (503 drugs)
Browse all the conditions that are associated with Ocular icterus:
- Ocular icterus (783 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on allopurinol (the active ingredients of Allopurinol) and Allopurinol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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