Allopurinol and Pustular psoriasis - a phase IV clinical study of FDA data

Summary:

Pustular psoriasis is reported as a side effect among people who take Allopurinol (allopurinol), especially for people who are female, 60+ old, also take Humira, and have Psoriasis.

The phase IV clinical study analyzes which people have Pustular psoriasis when taking Allopurinol. It is created by eHealthMe based on reports of 188,106 people who have side effects when taking Allopurinol from the FDA, and is updated regularly.

What is Allopurinol?

Allopurinol has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,869 Allopurinol users. Check the latest studies of Allopurinol.

What is Pustular psoriasis?

Pustular psoriasis (raised bumps on the skin that are filled with pus) is found to be associated with 257 drugs and 416 conditions by eHealthMe. Check the latest studies of Pustular psoriasis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

188,106 people reported to have side effects when taking Allopurinol.
Among them, 26 people (0.01%) have Pustular psoriasis.

Could Allopurinol cause Pustular psoriasis?

Among these 26 people:

What is the gender of people who have Pustular psoriasis when taking Allopurinol? *

female: 60 %
male: 40 %

What is the age of people who have Pustular psoriasis when taking Allopurinol? *

What are other drugs people take besides Allopurinol? *

What are other side effects people have besides Pustular psoriasis? *

Abdominal Discomfort: 5 people, 19.23%
Hypoproteinaemia (too little prolactin circulating in the blood): 4 people, 15.38%
Joint Pain: 4 people, 15.38%
Sepsis (a severe blood infection that can lead to organ failure and death): 4 people, 15.38%
Renal Impairment (severely reduced kidney function): 4 people, 15.38%
Rashes (redness): 3 people, 11.54%
Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 3 people, 11.54%
Headache (pain in head): 3 people, 11.54%
Henoch-Schonlein Purpura (inflammation of the blood vessels in the skin and other body organs): 3 people, 11.54%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 3 people, 11.54%

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 5 people, 19.23%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 4 people, 15.38%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 4 people, 15.38%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 11.54%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 11.54%
Blood Uric Acid Increased: 3 people, 11.54%
Cardiac Failure: 3 people, 11.54%
High Blood Pressure: 3 people, 11.54%
Hypokalemia (low potassium): 2 people, 7.69%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Allopurinol and have Pustular psoriasis?

- Check whether Pustular psoriasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Allopurinol:

Allopurinol (190,869 reports)

Browse all side effects of Allopurinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pustular psoriasis:

Pustular psoriasis (257 drugs)

Browse all the conditions that are associated with Pustular psoriasis:

Pustular psoriasis (416 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Allopurinol) and Allopurinol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.