Allopurinol and Social avoidant behavior - a phase IV clinical study of FDA data

Summary:

Social avoidant behavior is reported as a side effect among people who take Allopurinol (allopurinol), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Digoxin, and have Enlarged prostate.

The phase IV clinical study analyzes which people have Social avoidant behavior when taking Allopurinol. It is created by eHealthMe based on reports of 188,106 people who have side effects when taking Allopurinol from the FDA, and is updated regularly.

What is Allopurinol?

Allopurinol has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,869 Allopurinol users. Check the latest studies of Allopurinol.

What is Social avoidant behavior?

Social avoidant behavior is found to be associated with 475 drugs and 618 conditions by eHealthMe. Check the latest studies of Social avoidant behavior.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

188,106 people reported to have side effects when taking Allopurinol.
Among them, 44 people (0.02%) have Social avoidant behavior.

Could Allopurinol cause Social avoidant behavior?

Among these 44 people:

How long have people been on Allopurinol when they have Social avoidant behavior? *

What is the gender of people who have Social avoidant behavior when taking Allopurinol? *

female: 34.09 %
male: 65.91 %

What is the age of people who have Social avoidant behavior when taking Allopurinol? *

What are other drugs people take besides Allopurinol? *

What are other side effects people have besides Social avoidant behavior? *

Weakness: 26 people, 59.09%
Fatigue (feeling of tiredness): 20 people, 45.45%
Depression: 19 people, 43.18%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 17 people, 38.64%
Dyspnea (difficult or laboured breathing): 16 people, 36.36%
Dizziness: 16 people, 36.36%
Diarrhea: 16 people, 36.36%
Disturbance In Attention: 14 people, 31.82%
Indigestion: 14 people, 31.82%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 29.55%

What are the existing conditions these people have? *

High Blood Pressure: 7 people, 15.91%
Signet-Ring Cell Carcinoma (signet cell cancer tumour): 7 people, 15.91%
Pain: 7 people, 15.91%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 7 people, 15.91%
Enlarged Prostate: 7 people, 15.91%
Affective Disorder (mental disorder): 6 people, 13.64%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 13.64%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 13.64%
Bipolar Disorder (mood disorder): 6 people, 13.64%
Cardiac Failure Chronic: 6 people, 13.64%

* Approximation only. Some reports may have incomplete information.

Do you take Allopurinol and have Social avoidant behavior?

- Check whether Social avoidant behavior is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Allopurinol:

Allopurinol (190,869 reports)

Browse all side effects of Allopurinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Social avoidant behavior:

Social avoidant behavior (475 drugs)

Browse all the conditions that are associated with Social avoidant behavior:

Social avoidant behavior (618 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Allopurinol) and Allopurinol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.